Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13716981 | 0.91 | SIRT1 (0.35) | SIRT5CA1CA2SIRT1SIRT2 | |
| SCHEMBL13717184 | 0.86 | SIRT1 (0.35) | SIRT5SIRT1SIRT2HDAC1SIRT3 | |
| SCHEMBL13717154 | 0.83 | SIRT5 (0.33) | SIRT5CA1CA2SIRT1SIRT2 | |
| SCHEMBL13717194 | 0.81 | SIRT5 (0.37) | SIRT5SIRT1SIRT2HDAC4HDAC1 | |
| SCHEMBL13716996 | 0.79 | SIRT1 (0.45) | SIRT5SIRT1SIRT2SIRT3 | |
| SCHEMBL13820111 | 0.76 | LTA4H (0.44) | — | |
| SCHEMBL13820179 | 0.76 | LTA4H (0.44) | — | |
| SCHEMBL13820104 | 0.76 | GRM5 (0.38) | SMN1; SMN2 | |
| SCHEMBL13717238 | 0.76 | RAB9A (0.33) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL13717545 | 0.76 | LTA4H (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927728-B2 | Dipeptide acetylene conjugates and a method for photocleavage of double strand DNA by dipeptide acetylene conjugates | The Florida State University Research Foundation, Inc. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20120288940-A1 | DIPEPTIDE ACETYLENE CONJUGATES AND A METHOD FOR PHOTOCLEAVAGE OF DOUBLE STRAND DNA BY DIPEPTIDE ACETYLENE CONJUGATES | The Florida State University Research Foundation, Inc. (US) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120288940-A1 | DIPEPTIDE ACETYLENE CONJUGATES AND A METHOD FOR PHOTOCLEAVAGE OF DOUBLE STRAND DNA BY DIPEPTIDE ACETYLENE CONJUGATES | DNPEP, DCLRE1A, PCNA | SIRT5 1981/4885CA1 572/4885CA2 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.