Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13717184 | 0.87 | SIRT1 (0.35) | SIRT5SIRT1HDAC1FOLH1SIRT2 | |
| SCHEMBL13717245 | 0.83 | SIRT5 (0.41) | SIRT5SIRT1HDAC1CA1CA2 | |
| SCHEMBL13716981 | 0.83 | SIRT1 (0.35) | SIRT5SIRT1CA1CA2FOLH1 | |
| SCHEMBL13717194 | 0.81 | SIRT5 (0.37) | SIRT5SIRT1HDAC1FOLH1SIRT2 | |
| SCHEMBL13820151 | 0.80 | TERT (0.39) | KMT2AMEN1 | |
| SCHEMBL13820144 | 0.76 | AAK1 (0.32) | KMT2AMEN1 | |
| SCHEMBL13820149 | 0.76 | ROCK2 (0.34) | KMT2AMEN1 | |
| SCHEMBL13820172 | 0.75 | TERT (0.39) | — | |
| SCHEMBL13717238 | 0.75 | RAB9A (0.33) | KMT2AMEN1 | |
| SCHEMBL13827497 | 0.67 | CA1 (0.47) | SIRT5KMT2ASIRT1HDAC1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927728-B2 | Dipeptide acetylene conjugates and a method for photocleavage of double strand DNA by dipeptide acetylene conjugates | The Florida State University Research Foundation, Inc. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20120288940-A1 | DIPEPTIDE ACETYLENE CONJUGATES AND A METHOD FOR PHOTOCLEAVAGE OF DOUBLE STRAND DNA BY DIPEPTIDE ACETYLENE CONJUGATES | The Florida State University Research Foundation, Inc. (US) | 2012-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120288940-A1 | DIPEPTIDE ACETYLENE CONJUGATES AND A METHOD FOR PHOTOCLEAVAGE OF DOUBLE STRAND DNA BY DIPEPTIDE ACETYLENE CONJUGATES | DNPEP, DCLRE1A, PCNA | SIRT5 1981/4885KMT2A 1160/4885SIRT1 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.