SCHEMBL13718

SCHEMBL13718

CC1(C)OB(c2ccc3cc[nH]c3c2)OC1(C)C

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LPL P06858 10/20 0.46
LIPG Q9Y5X9 10/20 0.46
MEN1 O00255 1/20 0.42
POLB P06746 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
AHR P35869 3/20 0.42
CMA1 P23946 1/20 0.42
TYR P14679 1/20 0.42
ENPP2 Q13822 2/20 0.39
IRAK4 Q9NWZ3 1/20 0.39
CYP2A6 P11509 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
BRD4 O60885 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29513455 1.00 LPL (0.46) LPLLIPGMEN1POLBMAPK1
SCHEMBL19335428 0.87 LPL (0.37) LPLLIPGMEN1POLBMAPK1
SCHEMBL9918 0.87 LPL (0.43) LPLLIPGAHRCYP2A6
SCHEMBL30052604 0.87 LPL (0.43) LPLLIPGAHRCYP2A6
SCHEMBL19669343 0.84 MEN1 (0.38) LPLLIPGMEN1POLBMAPK1
SCHEMBL3195954 0.81 AHR (0.43) MEN1POLBMAPK1KMT2AAHR
SCHEMBL3792136 0.78 LIPG (0.60) LPLLIPGBRD4
SCHEMBL31304657 0.78 LPL (0.42) LPLLIPGIRAK4
SCHEMBL2171645 0.78 LPL (0.42) LPLLIPGIRAK4
SCHEMBL29644319 0.78 LPL (0.62) LPLLIPGIRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10981867-B2 EBNA1 inhibitors and methods using same THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) 2021-04-20 US claimed
US-20200239415-A1 EBNA1 INHIBITORS AND METHODS USING SAME WISTAR INST (US) 2020-07-30 US claimed
US-7507262-B2 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY (US) 2009-03-24 US claimed
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY 2007-09-13 US claimed
US-20250353830-A1 NOVEL COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 2025-11-20 US disclosed
US-12466813-B2 PRC1 inhibitors and methods of treatment therewith THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2025-11-11 US disclosed
US-12435091-B2 RNA-binding protein multimerization inhibitors and methods of use thereof THE UAB RESEARCH FOUNDATION (US) 2025-10-07 US disclosed
EP-4155293-B1 PRC1 INHIBITORS AND METHODS OF TREATMENT THEREWITH UNIV MICHIGAN REGENTS (US) 2025-07-30 EP disclosed
WO-2025137158-A1 DERIVATIVES OF ([1,2,4]TRIAZOLO[5,1-A]ISOQUINOLINE-5-CARBONYL)GLYCINATE AS PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE AKEBIA THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
US-20250179075-A1 MK2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-06-05 US disclosed
EP-4531858-A1 NOVEL COMPOUNDS F. Hoffmann-La Roche AG (CH) 2025-04-09 EP disclosed
US-20250063947-A1 COMPOUND AND ITS USE IN ORGANIC ELECTRONIC DEVICES HELIATEK GMBH (DE) 2025-02-20 US disclosed
US-20090144914-A1 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS LIM MU LLL 2009-06-11 US disclosed
US-7507262-B2 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY (US) 2009-03-24 US disclosed
US-20070282101-A1 Indazole compounds ABBVIE INC. 2007-12-06 US disclosed
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions THE PROCTER & GAMBLE COMPANY 2007-09-13 US disclosed
EP-1730116-B1 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS SMITHKLINE BEECHAM CORP (US) 2007-09-05 EP disclosed
US-20070167507-A1 4-Carbox pyrazole derivatives useful as anti-viral agents GLAXO GROUP LIMITED (GB) 2007-07-19 US disclosed
EP-1730116-A1 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS SMITHKLINE BEECHAM CORPORATION (US) 2006-12-13 EP disclosed
WO-2005092863-A1 4-CARBOX PYRAZOLE DERIVATES USEFUL AS ANTI-VIRAL AGENTS SMITHKLINE BEECHAM CORPORATION (US) 2005-10-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200239415-A1 EBNA1 INHIBITORS AND METHODS USING SAME MLLT1, EBNA1BP2, MALT1 LPL 2143/4885LIPG 2380/4885MEN1 30/4885
US-20070282101-A1 Indazole compounds CYP3A43, CYP3A7, UGT1A1 LPL 3658/4885LIPG 3363/4885MEN1 878/4885
US-12466813-B2 PRC1 inhibitors and methods of treatment therewith BMI1, EZH2, CBX3 LPL 3771/4885LIPG 3523/4885MEN1 1186/4885
US-10981867-B2 EBNA1 inhibitors and methods using same MLLT1, EBNA1BP2, MALT1 LPL 2143/4885LIPG 2380/4885MEN1 30/4885
US-20250353830-A1 NOVEL COMPOUNDS UQCRB, CCNB3, C5 LPL 3010/4885LIPG 3163/4885MEN1 825/4885
US-20090144914-A1 COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS KRT18, AKR7A2, AKR1C4 LPL 3490/4885LIPG 3289/4885MEN1 4624/4885
US-12435091-B2 RNA-binding protein multimerization inhibitors and methods of use thereof HNRNPR, HNRNPAB, RBM3 LPL 2910/4885LIPG 2079/4885MEN1 2806/4885
US-20250063947-A1 COMPOUND AND ITS USE IN ORGANIC ELECTRONIC DEVICES CYP2C19, CYP2C9, CYP2E1 LPL 4428/4885LIPG 2506/4885MEN1 799/4885
US-20070209123-A1 Compositions for oxidatively dyeing keratin fibers and methods for using such compositions KRT18, AKR7A2, AKR1C4 LPL 3490/4885LIPG 3289/4885MEN1 4624/4885
US-20070167507-A1 4-Carbox pyrazole derivatives useful as anti-viral agents HAVCR2, RPL35, ZC3HAV1L LPL 1506/4885LIPG 1396/4885MEN1 4820/4885
US-20250179075-A1 MK2 DEGRADERS AND USES THEREOF MKNK2, MKRN3, DUS2 LPL 1450/4885LIPG 2704/4885MEN1 1917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.