Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21578106 | 0.84 | ALDH1A1 (0.65) | ALDH1A1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL1506643 | 0.82 | ALDH1A1 (0.62) | ALDH1A1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL16683011 | 0.78 | TDP1 (0.47) | ALDH1A1TDP1 | |
| SCHEMBL576605 | 0.77 | LMNA (0.39) | ALDH1A1TDP1TSHRCA12CA1 | |
| Biphenyl SCHEMBL5404337 | 0.76 | TSHR (0.44) | ALDH1A1TDP1TSHRSMN1; SMN2CA12 | |
| SCHEMBL13718321 | 0.76 | ALDH1A1 (0.54) | ALDH1A1ATMTDP1L3MBTL1SRD5A2 | |
| SCHEMBL13713552 | 0.76 | TSHR (0.43) | ALDH1A1TDP1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL7074393 | 0.76 | CA1 (0.37) | SMN1; SMN2CA12CA1CA2KMT2A | |
| SCHEMBL29671224 | 0.75 | HSD11B1 (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL7048111 | 0.75 | TSHR (0.67) | ALDH1A1TDP1TSHRSMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089988-B1 | FLUOROPHENYL RESIN COMPOUNDS | AVENTIS PHARMA INC (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1044364-B1 | METHOD FOR THE QUANTIFICATION OF SOLID-PHASE REACTIONS USING FLUORINE NMR | AVENTIS PHARM PROD INC (US) | 2007-06-13 | — | — | EP | disclosed |