Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27341210 | 0.83 | ALDH1A1 (0.37) | SOAT1ALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL8913069 | 0.79 | — | — | |
| SCHEMBL1370094 | 0.78 | NPSR1 (0.37) | SOAT1ALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL27752055 | 0.77 | — | — | |
| SCHEMBL2204826 | 0.76 | ALDH1A1 (0.43) | SOAT1ALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL1370917 | 0.74 | — | — | |
| SCHEMBL2255510 | 0.74 | SOAT1 (0.39) | SOAT1ALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL18512590 | 0.73 | — | — | |
| SCHEMBL2927909 | 0.73 | — | — | |
| SCHEMBL3281705 | 0.71 | EGLN1 (0.39) | SOAT1ALDH1A1NPSR1GLO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103193662-A | Method for preparing Beta-amino ester through copper-catalyzed three-component coupling reaction | UNIV BEIJING SCIENCE & TECH | 2013-07-10 | — | — | CN | claimed |
| CN-110423198-B | Acid catalysis synthesis method and application of phenoxyl acetate derivative | 南京师范大学 | 2022-03-25 | — | — | CN | disclosed |
| US-10934531-B2 | Method for enantioselective carbene C—H insertion using an iron-containing protein catalyst | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| US-10927355-B2 | Method for producing an organosilicon product | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-02-23 | — | — | US | disclosed |
| US-20190276805-A1 | METHOD FOR ENANTIOSELECTIVE CARBENE C-H INSERTION USING AN IRON-CONTAINING PROTEIN CATALYST | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-09-12 | — | — | US | disclosed |
| WO-2019147865-A1 | A METHOD FOR ENANTIOSELECTIVE CARBENE C-H INSERTION USING AN IRON-CONTAINING PROTEIN CATALYST | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-08-01 | — | — | WO | disclosed |
| US-20180371430-A1 | Heme Protein Catalysts for Carbon-Silicon Bond Formation In Vitro and In Vivo | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-12-27 | — | — | US | disclosed |
| US-10093906-B2 | Cytochrome C protein variants for catalyzing carbon-silicon bond formation | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-10-09 | — | — | US | disclosed |
| US-20180186827-A1 | Ectonucleotidase Inhibitors and Methods of Use Thereof | ANTENGENE THERAPEUTICS LIMITED (CN) | 2018-07-05 | — | — | US | disclosed |
| US-20180072742-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | ANTENGENE THERAPEUTICS LIMITED (CN) | 2018-03-15 | — | — | US | disclosed |
| CN-103193662-A | Method for preparing Beta-amino ester through copper-catalyzed three-component coupling reaction | UNIV BEIJING SCIENCE & TECH | 2013-07-10 | — | — | CN | disclosed |
| US-8283353-B2 | Fused ring compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-10-09 | — | — | US | disclosed |
| CN-102369205-A | Fused ring compound and use thereof | TAKEDA PHARMACEUTICAL | 2012-03-07 | — | — | CN | disclosed |
| US-20110294832-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-12-01 | — | — | US | disclosed |
| US-20110288087-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-11-24 | — | — | US | disclosed |
| EP-2384327-A1 | FUSED RING COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| WO-2010087515-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |
| US-20100197683-A1 | FUSED RING COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2010-08-05 | — | — | US | disclosed |
| WO-1991002526-A1 | AZABICYCLO QUINOLONE CARBOXYLIC ACIDS | PFIZER INC. (US) | 1991-03-07 | — | — | WO | disclosed |
| US-4525201-A | PLANT GROWTH REGULATORS | SHELL OIL COMPANY (US) | 1985-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186827-A1 | Ectonucleotidase Inhibitors and Methods of Use Thereof | NT5E, ENTPD5, NT5C2 | SOAT1 3309/4885ALDH1A1 527/4885NPSR1 199/4885 |
| US-10093906-B2 | Cytochrome C protein variants for catalyzing carbon-silicon bond formation | CYC1, HCCS, COX6C | SOAT1 3216/4885ALDH1A1 4512/4885NPSR1 3123/4885 |
| US-20110288087-A1 | FUSED RING COMPOUND AND USE THEREOF | PPARA, PPARG, AGTR2 | SOAT1 598/4885ALDH1A1 1050/4885NPSR1 813/4885 |
| US-20110294832-A1 | FUSED RING COMPOUND AND USE THEREOF | PPARA, PPARG, AGTR2 | SOAT1 598/4885ALDH1A1 1050/4885NPSR1 813/4885 |
| US-20180072742-A1 | ECTONUCLEOTIDASE INHIBITORS AND METHODS OF USE THEREOF | NT5E, ENTPD5, NT5C2 | SOAT1 3309/4885ALDH1A1 527/4885NPSR1 199/4885 |
| US-20100197683-A1 | FUSED RING COMPOUND AND USE THEREOF | PPARA, PPARG, AGTR2 | SOAT1 598/4885ALDH1A1 1050/4885NPSR1 813/4885 |
| US-10927355-B2 | Method for producing an organosilicon product | HMOX2, HMOX1, HMBS | SOAT1 2702/4885ALDH1A1 4117/4885NPSR1 2286/4885 |
| US-20180371430-A1 | Heme Protein Catalysts for Carbon-Silicon Bond Formation In Vitro and In Vivo | HMOX2, HMOX1, HCCS | SOAT1 2731/4885ALDH1A1 4449/4885NPSR1 3174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.