SCHEMBL1372572

SCHEMBL1372572

Nc1cc(-c2ccc3c(c2-c2ccc(O)c(N)c2)Cc2ccccc2-3)ccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.45
KDM4E B2RXH2 2/20 0.45
ALDH1A1 P00352 2/20 0.45
LMNA P02545 2/20 0.45
MAPT P10636 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
USP2 O75604 1/20 0.45
HSP90AA1 P07900 1/20 0.45
GAA P10253 1/20 0.45
ALOX15 P16050 1/20 0.45
ALOX12 P18054 1/20 0.45
HTT P42858 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PNMT P11086 1/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
APP P05067 1/20 0.38
ADORA2A P29274 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29800533 1.00 HPGD (0.45) HPGDKDM4EALDH1A1LMNAMAPT
SCHEMBL20483771 0.89 CYP3A4 (0.43) HPGDKDM4EALDH1A1LMNAMAPT
SCHEMBL28067835 0.87 KDM4E (0.46) HPGDKDM4EALDH1A1LMNAMAPT
SCHEMBL30036609 0.87 APP (0.53) HPGDKDM4EALDH1A1LMNAMAPT
SCHEMBL28847551 0.87 APP (0.53) HPGDKDM4EALDH1A1LMNAMAPT
SCHEMBL4640228 0.87 ALDH1A1 (0.49) HPGDKDM4EALDH1A1LMNAMAPT
SCHEMBL30385603 0.83 PNMT (0.38) HPGDKDM4EALDH1A1LMNAMAPT
SCHEMBL29921844 0.83 TLR8 (0.42) HPGDKDM4EALDH1A1LMNAMAPT
SCHEMBL29800244 0.83 PGR (0.41) HPGDKDM4EALDH1A1LMNAMAPT
SCHEMBL5717486 0.83 TLR8 (0.42) HPGDKDM4EALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024216910-A1 HIGH-CHEMICAL-RESISTANCE POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 明士(北京)新材料开发有限公司 2024-10-24 WO claimed
CN-118108661-B Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof 波米科技有限公司 2024-09-20 CN claimed
CN-118108661-A Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof 波米科技有限公司 2024-05-31 CN claimed
CN-114524938-B Polymer, photosensitive resin composition, cured film prepared from polymer and photosensitive resin composition, and electronic element 江苏三月科技股份有限公司 2024-02-09 CN claimed
CN-116836389-B Low-temperature-curable positive photosensitive resin, resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2024-01-26 CN claimed
CN-114230792-B Positive photosensitive polyimide resin, resin composition, and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-10-03 CN claimed
CN-116836389-A Low-temperature-curable positive photosensitive resin, resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2023-10-03 CN claimed
CN-116149140-B Positive photosensitive resin composition with high chemical resistance and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-07-14 CN claimed
CN-116068852-B Positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-07-14 CN claimed
CN-116149140-A Positive photosensitive resin composition with high chemical resistance and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-05-23 CN claimed
CN-114995061-B Low-water-absorption positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-11-01 CN claimed
CN-115220305-A Positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-10-21 CN claimed
CN-114995061-A Low-water-absorption positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-09-02 CN claimed
CN-114524938-A Polymer, photosensitive resin composition, cured film prepared from same and electronic element 江苏三月科技股份有限公司 2022-05-24 CN claimed
WO-2022068900-A1 POSITIVE PHOTOSENSITIVE POLYAMIDE ESTER RESIN AND COMPOSITION USING SAME 明士(北京)新材料开发有限公司 2022-04-07 WO claimed
CN-114230792-A Positive photosensitive polyimide resin, resin composition, and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-03-25 CN claimed
CN-112876679-A Positive photosensitive polyamide compound and application thereof 中节能万润股份有限公司 2021-06-01 CN claimed
CN-112175182-A Positive photosensitive polyesteramide resin and composition using same 明士(北京)新材料开发有限公司 2021-01-05 CN claimed
CN-111522201-A Positive photosensitive resin composition, cured film prepared from positive photosensitive resin composition and electronic element 江苏三月科技股份有限公司 2020-08-11 CN claimed
CN-109270792-A A kind of high tenacity, high heat resistance, can weak base water development polyimides/photosensitive epoxy acrylic resin composition 浙江福斯特新材料研究院有限公司 2019-01-25 CN claimed