SCHEMBL5717486

SCHEMBL5717486

Cc1cc(-c2ccc3c(c2-c2ccc(O)c(C)c2)Cc2ccccc2-3)ccc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.42
PGR P06401 1/20 0.41
HSD17B1 P14061 3/20 0.39
HSD17B2 P37059 3/20 0.39
ESR2 Q92731 2/20 0.38
PNMT P11086 1/20 0.38
MCL1 Q07820 1/20 0.38
APP P05067 1/20 0.38
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
ESR1 P03372 1/20 0.36
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30314491 1.00 TLR8 (0.42) TLR8PGRHSD17B1HSD17B2ESR2
SCHEMBL29921844 1.00 TLR8 (0.42) TLR8PGRHSD17B1HSD17B2ESR2
SCHEMBL28847551 0.87 APP (0.53) PGRPNMTAPPNPC1RAB9A
SCHEMBL30036609 0.87 APP (0.53) PGRPNMTAPPNPC1RAB9A
SCHEMBL918080 0.87 TLR8 (0.48) TLR8HSD17B1HSD17B2ESR2PNMT
SCHEMBL31046749 0.83 PGR (0.44) PGRPNMTNPC1RAB9ACYP3A4
SCHEMBL30385603 0.83 PNMT (0.38) PGRESR2PNMTAPPNPC1
SCHEMBL29800533 0.83 HPGD (0.45) PGRPNMTMCL1APPNPC1
SCHEMBL1372572 0.83 HPGD (0.45) PGRPNMTMCL1APPNPC1
SCHEMBL7919926 0.83 PGR (0.44) PGRPNMTNPC1RAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109836565-A A kind of siloxane copolycarbonate and preparation method thereof 万华化学集团股份有限公司 2019-06-04 CN claimed
CN-104950577-B Photosensitive resin composition for light-shielding film, light-shielding film obtained by curing the same, and color filter 日铁化学材料株式会社 2019-12-03 CN disclosed
CN-104423153-B The manufacturing method of gate insulating film, Organic Thin Film Transistors and Organic Thin Film Transistors 日铁化学材料株式会社 2019-11-05 CN disclosed
CN-110402270-A Flame-retardant polycarbonate resin composition and molded article thereof IDEMITSU KOSAN CO 2019-11-01 CN disclosed
CN-110382623-A Polycarbonate resin composition and molded article thereof 出光兴产株式会社 2019-10-25 CN disclosed
CN-110382593-A Polycarbonate-polyorganosiloxane copolymer, polycarbonate resin composition containing same, and molded article thereof 出光兴产株式会社 2019-10-25 CN disclosed
CN-110382624-A Polycarbonate resin composition and molded article thereof 出光兴产株式会社 2019-10-25 CN disclosed
CN-110366573-A Polycarbonate-polyorganosiloxane copolymer, polycarbonate resin composition containing same, and molded article thereof 出光兴产株式会社 2019-10-22 CN disclosed
CN-110366574-A Polycarbonate-polyorganosiloxane copolymer, flame-retardant polycarbonate resin composition containing same, and molded article thereof 出光兴产株式会社 2019-10-22 CN disclosed
CN-110343241-A Thermosetting resin composition, followability piece, hardening thing and printing distributing board 东洋油墨SC控股株式会社 2019-10-18 CN disclosed
CN-108363276-A Electrophtography photosensor, handle box and image forming apparatus 京瓷办公信息系统株式会社 2018-08-03 CN disclosed
CN-108367529-A Light flame-retardant thermoplastic structure 施内勒公司 2018-08-03 CN disclosed
CN-108290828-A Oxime ester compound having excellent thermal stability, photopolymerization initiator containing the same, and photosensitive resin composition 京仁洋行股份有限公司 2018-07-17 CN disclosed
CN-101048679-A Infrared absorbing filter OSAKA GAS CO LTD (JP) 2007-10-03 CN disclosed
CN-1926172-A Aromatic polycarbonate resin composition and process for producing the same TEIJIN CHEMICALS LTD (JP) 2007-03-07 CN disclosed
EP-1671202-A2 KIOSK AND METHOD FOR DELIVERING SELECTED DIGITAL CONTENT GENERAL ELECTRIC COMPANY (US) 2006-06-21 EP disclosed
JP-2005212820-A ELECTRONIC COMPONENT TRANSFER CONTAINER TEIJIN CHEM LTD 2005-08-11 JP disclosed
WO-2005024608-A2 KIOSK AND METHOD FOR DELIVERING SELECTED DIGITAL CONTENT GENERAL ELECTRIC COMPANY (US) 2005-03-17 WO disclosed
EP-0274209-A1 Glycidylethers of fluorene-containing bisphenols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-07-13 EP disclosed
US-4707534-A PROTECTIVE COATINGS, POLYEPOXIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-11-17 US disclosed