SCHEMBL13726323

SCHEMBL13726323

Cc1cccc([N+]#N)c1C.F[B-](F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.37
ATM Q13315 1/20 0.37
ACHE P22303 2/20 0.34
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13824679 0.91 TRPA1 (0.42) TRPA1ATMACHECYP1A2CYP2A6
Bromide SCHEMBL26115689 0.89 TRPA1 (0.41) TRPA1ATMACHECYP1A2CYP2A6
Hydrochloric Acid SCHEMBL11681962 0.89 TRPA1 (0.41) TRPA1ATMACHECYP1A2CYP2A6
SCHEMBL11522076 0.83 ACHE (0.42) ACHECYP2A6CYP3A4TSHRSMN1; SMN2
Ammonia Solution, Strong SCHEMBL29141774 0.81 ACHE (0.41) ACHECYP3A4TSHRCA1CA2
SCHEMBL4113607 0.80 ALDH1A1 (0.32) ALDH1A1
SCHEMBL28772799 0.79 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11526486 0.77 TAS2R14 (0.38) ACHE
SCHEMBL31619912 0.76 ACHE (0.39) TRPA1ATMACHECYP1A2CYP2A6
SCHEMBL27322547 0.74 ACHE (0.37) TRPA1ATMACHECYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012150281-A1 PREPARATION OF 3,3-DIALKXOY-1-METHYLENEPROPYL ARENES LONZA LTD (CH) 2012-11-08 WO disclosed
WO-2012150280-A2 PREPARATION OF 4,4-DIALKOXY-1-BUTEN-1-YLARENES LONZA LTD (CH) 2012-11-08 WO disclosed