SCHEMBL13726902

SCHEMBL13726902

CCN1C(=O)C(=Cc2cc(Br)ccc2O)SC1=S

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDE4B Q07343 2/20 0.58
▸ MEN1 O00255 8/20 0.55
▸ KMT2A Q03164 8/20 0.55
▸ ALDH1A1 P00352 5/20 0.55
▸ MAPT P10636 3/20 0.55
▸ NPC1 O15118 1/20 0.55
▸ LMNA P02545 1/20 0.55
▸ IDE P14735 1/20 0.55
▸ ALOX12 P18054 1/20 0.55
▸ TNNI3 P19429 1/20 0.55
▸ TNNT2 P45379 1/20 0.55
▸ RAB9A P51151 1/20 0.55
▸ TNNC1 P63316 1/20 0.55
▸ PTP4A3 O75365 1/20 0.54
▸ DDX3X O00571 1/20 0.53
▸ POLB P06746 4/20 0.53
▸ HSD17B3 P37058 3/20 0.50
▸ BLM P54132 1/20 0.49
▸ NSD2 O96028 1/20 0.48
▸ PLA2G1B P04054 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13726901 1.00 PDE4B (0.58) PDE4BMEN1KMT2AALDH1A1MAPT
SCHEMBL15761663 0.86 MEN1 (0.59) PDE4BMEN1KMT2AALDH1A1MAPT
SCHEMBL16218029 0.83 PDE4B (0.62) PDE4BMEN1KMT2AALDH1A1MAPT
SCHEMBL16210973 0.83 PDE4B (0.62) PDE4BMEN1KMT2AALDH1A1MAPT
SCHEMBL16210975 0.83 PDE4B (0.62) PDE4BMEN1KMT2AALDH1A1MAPT
SCHEMBL13779295 0.80 PDE4B (0.58) PDE4BMEN1KMT2AALDH1A1MAPT
SCHEMBL7859655 0.79 MEN1 (0.51) PDE4BMEN1KMT2AALDH1A1MAPT
SCHEMBL14777216 0.79 PDE4B (0.76) PDE4BMEN1KMT2AALDH1A1MAPT
SCHEMBL14777217 0.79 PDE4B (0.76) PDE4BMEN1KMT2AALDH1A1MAPT
SCHEMBL7859591 0.78 MEN1 (0.50) PDE4BMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2704578-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF Inscent, Inc. (US) 2014-03-12 — — EP claimed
WO-2012151556-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF INSCENT, INC. (US) 2012-11-08 — — WO claimed
US-11963527-B2 Compounds, compositions, and methods for altering insect and organism behavior BASF CORPORATION (US) 2024-04-23 — — US disclosed
US-20190104732-A1 Compounds, Compositions, and Methods for Altering Insect and Organism Behavior BASF CORPORATION 2019-04-11 — — US disclosed
US-10098352-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2018-10-16 — — US disclosed
US-20160330960-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2016-11-17 — — US disclosed
US-9439434-B2 Honeybee repellents and uses thereof INSCENT, INC. (US) 2016-09-13 — — US disclosed
EP-2704578-B1 USE OF HONEYBEE REPELLENTS INSCENT INC (US) 2016-08-31 — — EP disclosed
EP-3027022-A2 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA, ARTICLE, AND/OR STRUCTURE Bayer CropScience LP (US) 2016-06-08 — — EP disclosed
US-20160029628-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA,ARTICLE, AND/OR STRUCTURE BAYER CROPSCIENCE LP (US) 2016-02-04 — — US disclosed
EP-2967041-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR Bayer CropScience LP (US) 2016-01-20 — — EP disclosed
US-20150257384-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR BASF CORPORATION 2015-09-17 — — US disclosed
WO-2014146143-A2 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA, ARTICLE, AND/OR STRUCTURE BAYER CROPSCIENCE LP (US) 2014-09-18 — — WO disclosed
WO-2014146145-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR BAYER CROPSCIENCE LP (US) 2014-09-18 — — WO disclosed
US-20140155261-A1 Honeybee Repellents and Uses Thereof INSCENT, INC. (US) 2014-06-05 — — US disclosed
EP-2704578-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF Inscent, Inc. (US) 2014-03-12 — — EP disclosed
WO-2012151556-A2 IMPROVED HONEYBEE REPELLENTS AND USES THEREOF INSCENT, INC. (US) 2012-11-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160029628-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR REPELLING AN INSECT FROM AN AREA,ARTICLE, AND/OR STRUCTURE ACHE, BCHE, SGMS1 PDE4B 847/4885MEN1 592/4885KMT2A 1629/4885
US-20160330960-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 PDE4B 2378/4885MEN1 2382/4885KMT2A 794/4885
US-10098352-B2 Honeybee repellents and uses thereof ACHE, AHNAK, L3MBTL3 PDE4B 2378/4885MEN1 2382/4885KMT2A 794/4885
US-11963527-B2 Compounds, compositions, and methods for altering insect and organism behavior ACHE, DDT, MGLL PDE4B 1504/4885MEN1 389/4885KMT2A 1063/4885
US-20150257384-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR ALTERING INSECT AND ORGANISM BEHAVIOR ACHE, DDT, MGLL PDE4B 1504/4885MEN1 389/4885KMT2A 1063/4885
US-20140155261-A1 Honeybee Repellents and Uses Thereof ACHE, AHNAK, L3MBTL3 PDE4B 2378/4885MEN1 2382/4885KMT2A 794/4885
US-20190104732-A1 Compounds, Compositions, and Methods for Altering Insect and Organism Behavior ACHE, DDT, MGLL PDE4B 1504/4885MEN1 389/4885KMT2A 1063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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