Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.57 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.57 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12866322 | 0.85 | PTPN12 (0.58) | MEN1KMT2AMAPTGFERPSMD14 | |
| SCHEMBL13236128 | 0.84 | PDE4B (0.53) | PDE4BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12008577 | 0.83 | PPARG (0.67) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL18857854 | 0.81 | MEN1 (0.68) | PDE4BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13727245 | 0.81 | MEN1 (0.68) | PDE4BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13727246 | 0.81 | MEN1 (0.68) | PDE4BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13726902 | 0.80 | PDE4B (0.58) | PDE4BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13726901 | 0.80 | PDE4B (0.58) | PDE4BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL18103095 | 0.80 | MEN1 (0.72) | PDE4BMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14777217 | 0.78 | PDE4B (0.76) | PDE4BMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | PRKCH, AIP, PRKCE | PDE4B 184/4885MEN1 4118/4885KMT2A 2487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.