Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | ELANE | P08246 | 3/20 | 0.49 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517555 | 0.87 | ELANE (0.49) | ELANECNR2KDM4EALDH1A1GAA | |
| SCHEMBL1375898 | 0.85 | AHR (0.61) | AHRCNR2KDM4EALDH1A1GAA | |
| SCHEMBL1375494 | 0.84 | MET (0.52) | ELANEKDM4EALDH1A1GAAHPGD | |
| SCHEMBL15334959 | 0.83 | CNR2 (0.49) | ELANECNR2KDM4EALDH1A1GAA | |
| SCHEMBL1423321 | 0.83 | LMNA (0.48) | ELANEKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL1374001 | 0.81 | CNR1 (0.59) | CNR2KDM4EALDH1A1GAAHPGD | |
| SCHEMBL1372639 | 0.81 | AHR (0.62) | AHRCNR2KDM4EALDH1A1CNR1 | |
| SCHEMBL17619480 | 0.80 | ELANE (0.43) | ELANECNR2KDM4EALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL1373594 | 0.80 | AHR (0.60) | AHRCNR2KDM4EALDH1A1CNR1 | |
| SCHEMBL1373592 | 0.80 | AHR (0.60) | AHRCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12479822-B2 | AHR agonists | ELI LILLY AND COMPANY (US) | 2025-11-25 | — | — | US | disclosed |
| EP-4402128-A1 | AHR AGONISTS | Eli Lilly and Company (US) | 2024-07-24 | — | — | EP | disclosed |
| CN-118215655-A | AHR agonists | 伊莱利利公司 | 2024-06-18 | — | — | CN | disclosed |
| US-20230159493-A1 | AHR AGONISTS | ELI LILLY AND COMPANY | 2023-05-25 | — | — | US | disclosed |
| WO-2023039275-A1 | AHR AGONISTS | ELI LILLY AND COMPANY (US) | 2023-03-16 | — | — | WO | disclosed |
| EP-2394995-B1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| EP-2394995-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | Kumiai Chemical Industry CO., LTD. (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159493-A1 | AHR AGONISTS | AHR, ARNT, RORC | AHR 1/4885ELANE 1418/4885CNR2 80/4885 |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | CBR3, CBR1, CHRM1 | AHR 376/4885ELANE 4755/4885CNR2 516/4885 |
| US-12479822-B2 | AHR agonists | AHR, ARNT, RORC | AHR 1/4885ELANE 1418/4885CNR2 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.