Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ADA | P00813 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13728292 | 0.82 | HTR2C (0.43) | AURKARPS6KB1LMNAHTR6 | |
| SCHEMBL13726844 | 0.78 | TDP1 (0.46) | MEN1KMT2APARP10AURKARPS6KB1 | |
| SCHEMBL13726969 | 0.78 | MAOB (0.46) | AURKARPS6KB1AURKB | |
| SCHEMBL13728466 | 0.77 | ADRA2A (0.60) | ALDH1A1HTTTDP1ADRA2AADRA2B | |
| SCHEMBL13728773 | 0.76 | P2RX3 (0.45) | — | |
| SCHEMBL13726397 | 0.76 | KCNA5 (0.43) | KMT2ALMNACYP1A2 | |
| SCHEMBL13729128 | 0.75 | CHEK2 (0.45) | TAAR1CYP2D6CYP1A2 | |
| SCHEMBL13728854 | 0.71 | NR3C2 (0.51) | AURKARPS6KB1HTR6 | |
| SCHEMBL3817879 | 0.71 | MEN1 (0.61) | MEN1KMT2APARP10ALDH1A1HTT | |
| SCHEMBL31389281 | 0.71 | MEN1 (0.61) | MEN1KMT2APARP10ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |