Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675967 | 0.76 | CHRNA7 (0.62) | ADORA3CHRNA7CASP3KDM4ENPC1 | |
| SCHEMBL13729610 | 0.76 | KIF11 (0.52) | ADORA3KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL1228649 | 0.75 | AURKA (0.49) | ADORA3AURKATPX2SCN5ANISCH | |
| SCHEMBL508237 | 0.72 | AURKA (0.57) | AURKATPX2SCN5AAKR1C2AKR1C1 | |
| SCHEMBL3664986 | 0.72 | CLK4 (0.57) | SCN5ABCHEACHENISCHKDM4E | |
| SCHEMBL19968789 | 0.71 | CASP3 (0.57) | CASP3NPC1MAPTRAB9A | |
| SCHEMBL254957 | 0.71 | MAPT (0.56) | NISCHKDM4EALDH1A1GAAMAPT | |
| SCHEMBL505538 | 0.70 | AURKA (0.69) | AURKATPX2AKR1C2AKR1C1ALDH1A1 | |
| SCHEMBL30046979 | 0.70 | AKR1C2 (0.44) | AURKATPX2SCN5AAKR1C2AKR1C1 | |
| SCHEMBL21001359 | 0.70 | ADORA3 (0.61) | ADORA3AURKATPX2AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |