Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30862210 | 0.83 | KIF11 (0.58) | KIF11CHUKTXNRD1NOX4ADORA3 | |
| SCHEMBL17269505 | 0.81 | KIF11 (0.62) | KIF11CHUKTXNRD1NOX4ADORA3 | |
| SCHEMBL7007719 | 0.80 | KIF11 (0.52) | KIF11CHUKTXNRD1NOX4ADORA3 | |
| SCHEMBL13729683 | 0.78 | ALDH1A1 (0.49) | CES2KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL18499136 | 0.78 | KCNH2 (0.48) | KIF11CHUKTXNRD1NOX4ADORA3 | |
| SCHEMBL13728793 | 0.76 | ADORA3 (0.49) | ADORA3KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL5249070 | 0.75 | TRPV3 (0.43) | KIF11CHUKTXNRD1NOX4ADORA3 | |
| SCHEMBL28465080 | 0.75 | KIF11 (0.71) | KIF11CHUKTXNRD1NOX4DPP4 | |
| SCHEMBL29712526 | 0.75 | KIF11 (0.71) | KIF11CHUKTXNRD1NOX4DPP4 | |
| SCHEMBL22497605 | 0.73 | KIF11 (0.48) | KIF11CHUKTXNRD1NOX4ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |