Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114509 | 0.87 | EGLN1 (0.58) | EGLN1ALDH1A1SMN1; SMN2POLBTHRB | |
| SCHEMBL31347371 | 0.80 | FAAH (0.56) | NPC1RAB9AALDH1A1POLBLMNA | |
| SCHEMBL31347381 | 0.75 | LMNA (0.52) | EGLN1ALDH1A1POLBHPGDLMNA | |
| SCHEMBL5127445 | 0.74 | NPC1 (0.53) | NPC1RAB9AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL31347377 | 0.74 | ALDH1A1 (0.55) | EGLN1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL31347376 | 0.74 | KMT2A (0.46) | EGLN1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL5117167 | 0.73 | LMNA (0.49) | EGLN1NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5129218 | 0.73 | HPGD (0.49) | EGLN1ALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL27697237 | 0.73 | L3MBTL1 (0.47) | EGLN1ALDH1A1POLBHPGDCA1 | |
| SCHEMBL31347373 | 0.73 | EGLN1 (0.42) | EGLN1NPC1RAB9ASMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371360-A | 5, 6-Dihydroxypyrimidine compound and preparation method and application thereof | 暨南大学 | 2025-01-28 | — | — | CN | disclosed |