Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34461785 | 0.85 | XDH (0.56) | KMT2AMEN1POLBNPC1SMN1; SMN2 | |
| SCHEMBL13726855 | 0.83 | L3MBTL1 (0.51) | MAP4K4POLBSCN9ANPC1CHEK2 | |
| SCHEMBL2543831 | 0.83 | HDAC6 (0.50) | KMT2AMEN1MAP4K4POLBSCN9A | |
| SCHEMBL29383595 | 0.83 | HDAC6 (0.50) | KMT2AMEN1MAP4K4POLBSCN9A | |
| SCHEMBL29961676 | 0.83 | NPC1 (0.56) | KMT2AMEN1MAP4K4SCN9AGRM2 | |
| SCHEMBL9081101 | 0.82 | ADORA3 (0.43) | KMT2AMAP4K4SCN9ASMN1; SMN2PIM1 | |
| SCHEMBL6650334 | 0.81 | KMO (0.49) | KMT2ANPC1PARP1MAP2K4 | |
| SCHEMBL6643741 | 0.81 | KMT2A (0.50) | KMT2AMEN1MAP4K4POLBNPC1 | |
| SCHEMBL3725622 | 0.80 | SCN9A (0.55) | KMT2AMAP4K4SCN9AIKBKBPARP1 | |
| SCHEMBL29961369 | 0.80 | SCN9A (0.47) | MAP4K4SCN9AGRM2XDHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |