Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144347 | 0.74 | ALOX15 (0.35) | FDPS | |
| SCHEMBL3663523 | 0.69 | ALDH1A1 (0.37) | FDPS | |
| SCHEMBL8671012 | 0.69 | FDPS (0.47) | FDPSCYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL6770012 | 0.68 | FDPS (0.38) | FDPSCYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL2093647 | 0.68 | FDPS (0.42) | FDPSCYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL24248595 | 0.67 | FDPS (0.37) | FDPSCYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL14003706 | 0.64 | FDPS (0.35) | FDPSCYP2D6CHRM2CHRM1CHRM3 | |
| SCHEMBL3432945 | 0.64 | LTB4R (0.39) | FDPS | |
| SCHEMBL17295659 | 0.64 | HDAC1 (0.39) | FDPS | |
| SCHEMBL8997963 | 0.63 | FDPS (0.41) | FDPSCYP2D6CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2701695-A2 | NEURODEGENERATIVE DISORDERS AND MUSCLE DISEASES IMPLICATING PUFAS | Retrotope, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2701697-A2 | OXIDATIVE RETINAL DISEASES | Retrotope, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2701698-A2 | DISORDERS IMPLICATING PUFA OXIDATION | Retrotope, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| EP-2701696-A2 | IMPAIRED ENERGY PROCESSING DISORDERS AND MITOCHONDRIAL DEFICIENCY | Retrotope, Inc. (US) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012148927-A2 | IMPAIRED ENERGY PROCESSING DISORDERS AND MITOCHONDRIAL DEFICIENCY | RETROTOPE, INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012148926-A2 | NEURODEGENERATIVE DISORDERS AND MUSCLE DISEASES IMPLICATING PUFAS | RETROTOPE, INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012148929-A2 | DISORDERS IMPLICATING PUFA OXIDATION | RETROTOPE, INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012148930-A2 | OXIDATIVE RETINAL DISEASES | RETROTOPE, INC. (US) | 2012-11-01 | — | — | WO | disclosed |