Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714336 | 0.81 | FDPS (0.40) | FDPSALDH1A1COPS5TSHRPKM | |
| SCHEMBL6770012 | 0.78 | FDPS (0.38) | FDPSCYP2C9ALDH1A1TSHRSLC6A3 | |
| SCHEMBL24248595 | 0.73 | FDPS (0.37) | FDPSCYP1A2CYP2C9ALDH1A1TSHR | |
| SCHEMBL992041 | 0.73 | FDPS (0.44) | FDPSALDH1A1COPS5TSHRSLC6A3 | |
| SCHEMBL8997963 | 0.73 | FDPS (0.41) | FDPSCYP1A2CYP2C9ALDH1A1COPS5 | |
| SCHEMBL19616053 | 0.73 | ALDH1A1 (0.36) | FDPSCYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL29470115 | 0.72 | FDPS (0.41) | FDPSALDH1A1TSHRPKMSLC6A3 | |
| SCHEMBL4574427 | 0.72 | ALDH1A1 (0.47) | FDPSALDH1A1COPS5TSHRPKM | |
| SCHEMBL16133682 | 0.71 | COPS5 (0.45) | FDPSALDH1A1COPS5PKMMEN1 | |
| SCHEMBL12752066 | 0.71 | PKM (0.38) | FDPSALDH1A1TSHRPKMTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231625-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | GlaxoSmithKline LLC (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009076140-A1 | THIAZOLE AND OXAZOLE KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |