Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.57 |
| ▸ | YAP1 | P46937 | 1/20 | 0.57 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.57 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13981698 | 0.85 | ALDH1A1 (0.59) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL1852593 | 0.84 | KMT2A (0.53) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL20659868 | 0.79 | TSHR (0.69) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL13741944 | 0.79 | ALDH1A1 (0.52) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL4099007 | 0.78 | TEAD1 (0.70) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL4102870 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL13741955 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL20659877 | 0.76 | TEAD1 (0.75) | ALDH1A1TEAD1YAP1TEAD4TEAD2 | |
| SCHEMBL13787069 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRHSD17B10MAPTTP53 | |
| SCHEMBL3118545 | 0.74 | ALDH1A1 (1.00) | ALDH1A1TEAD1YAP1TEAD4TEAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090214529-A9 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2009-08-27 | — | — | US | disclosed |
| US-20090214529-A9 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2009-08-27 | — | — | US | disclosed |
| US-20080292626-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-11-27 | — | — | US | disclosed |
| US-20080292626-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090214529-A9 | KINESIN INHIBITORS | KIF5B, KIF5A, KIF5C | ALDH1A1 1978/4885TEAD1 1557/4885YAP1 3950/4885 |
| US-20080292626-A1 | KINESIN INHIBITORS | KIF5B, KIF5A, KIF5C | ALDH1A1 1978/4885TEAD1 1557/4885YAP1 3950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.