Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.70 |
| ▸ | YAP1 | P46937 | 1/20 | 0.70 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.70 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20659877 | 0.85 | TEAD1 (0.75) | TEAD1YAP1TEAD4TEAD2HPGD | |
| SCHEMBL24845910 | 0.82 | TEAD1 (1.00) | TEAD1YAP1TEAD4TEAD2HPGD | |
| SCHEMBL20659868 | 0.80 | TSHR (0.69) | TEAD1YAP1TEAD4TEAD2HPGD | |
| SCHEMBL13981698 | 0.78 | ALDH1A1 (0.59) | TEAD1YAP1TEAD4TEAD2HPGD | |
| SCHEMBL13742016 | 0.78 | ALDH1A1 (0.59) | TEAD1YAP1TEAD4TEAD2HPGD | |
| SCHEMBL27351788 | 0.77 | HPGD (0.54) | TEAD1YAP1TEAD4TEAD2HPGD | |
| SCHEMBL1309765 | 0.76 | MAPK10 (0.64) | TEAD1YAP1TEAD4TEAD2HPGD | |
| SCHEMBL3118545 | 0.75 | ALDH1A1 (1.00) | TEAD1YAP1TEAD4TEAD2HPGD | |
| SCHEMBL30914152 | 0.74 | TEAD1 (0.62) | TEAD1YAP1TEAD4TEAD2HPGD | |
| SCHEMBL27238570 | 0.74 | TEAD1 (0.62) | TEAD1YAP1TEAD4TEAD2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090214529-A9 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2009-08-27 | — | — | US | disclosed |
| US-20090214529-A9 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2009-08-27 | — | — | US | disclosed |
| US-20090214529-A9 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2009-08-27 | — | — | US | disclosed |
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |
| WO-2008147852-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-12-04 | — | — | WO | disclosed |
| US-20080292626-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-11-27 | — | — | US | disclosed |
| US-20080292626-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-11-27 | — | — | US | disclosed |
| US-20080292626-A1 | KINESIN INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2008-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090214529-A9 | KINESIN INHIBITORS | KIF5B, KIF5A, KIF5C | TEAD1 1557/4885YAP1 3950/4885TEAD4 2089/4885 |
| US-20080292626-A1 | KINESIN INHIBITORS | KIF5B, KIF5A, KIF5C | TEAD1 1557/4885YAP1 3950/4885TEAD4 2089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.