SCHEMBL13745006

SCHEMBL13745006

CC(C)C[C@H]1C(=O)N(C2CCCCC2)C[C@H]2N1C(=O)N(C)N2C(=O)NCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.44
▸ HTT P42858 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ CLPP Q16740 1/20 0.44
▸ KMT2A Q03164 4/20 0.42
▸ HRH3 Q9Y5N1 1/20 0.41
▸ XIAP P98170 2/20 0.40
▸ GAA P10253 1/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ NPSR1 Q6W5P4 1/20 0.36
▸ AADAT Q8N5Z0 1/20 0.36
▸ FKBP1A P62942 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ CYP2C9 P11712 1/20 0.36
▸ PKM P14618 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL746316 0.88 CLPP (0.46) LMNAHTTSMN1; SMN2CLPPKMT2A
SCHEMBL746499 0.87 CLPP (0.47) LMNAHTTSMN1; SMN2CLPPKMT2A
SCHEMBL13500581 0.85 CLPP (0.46) LMNAHTTSMN1; SMN2CLPPKMT2A
SCHEMBL745490 0.82 LMNA (0.43) LMNAHTTSMN1; SMN2CLPPKMT2A
SCHEMBL748792 0.81 CLPP (0.44) LMNAHTTSMN1; SMN2CLPPKMT2A
SCHEMBL750246 0.80 ALDH1A1 (0.40) LMNAHTTSMN1; SMN2CLPPKMT2A
SCHEMBL749472 0.79 ALDH1A1 (0.41) LMNAHTTSMN1; SMN2CLPPKMT2A
SCHEMBL746320 0.78 LMNA (0.47) LMNAHTTSMN1; SMN2CLPPHRH3
SCHEMBL747720 0.77 LMNA (0.46) LMNAHTTSMN1; SMN2KMT2AHRH3
SCHEMBL746317 0.77 LMNA (0.46) LMNAHTTSMN1; SMN2CLPPKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 — — US disclosed
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION MYLK2, TNNC1, MYH2 LMNA 194/4885HTT 4301/4885SMN1; SMN2 103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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