Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 11/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204074 | 0.81 | ALDH1A1 (0.45) | SCARB1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL4029927 | 0.80 | SCARB1 (0.43) | SCARB1PTGDR2KDM4EALDH1A1GAA | |
| SCHEMBL4025431 | 0.80 | SCARB1 (0.46) | SCARB1PTGDR2KDM4EALDH1A1GAA | |
| SCHEMBL4033009 | 0.77 | SCARB1 (0.41) | SCARB1PTGDR2KDM4EALDH1A1GAA | |
| SCHEMBL4023327 | 0.76 | HSD17B10 (0.41) | SCARB1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL4031956 | 0.73 | THRB (0.42) | SCARB1 | |
| SCHEMBL13746919 | 0.72 | SCARB1 (0.57) | SCARB1PTGDR2KDM4EMEN1ALDH1A1 | |
| SCHEMBL13747863 | 0.69 | SCARB1 (0.46) | SCARB1PTGDR2KDM4EALDH1A1KMT2A | |
| SCHEMBL4027183 | 0.69 | SCARB1 (0.70) | SCARB1PTGDR2KDM4EMEN1ALDH1A1 | |
| SCHEMBL4025480 | 0.68 | SCARB1 (0.61) | SCARB1PTGDR2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103022-A1 | DERIVATIVES OF SUBSTITUTED FUSED RING CYCLOINDOLES AND METHODS OF THEIR USE | ITHERX PHARMACEUTICALS, INC. (US) | 2009-08-20 | — | — | WO | disclosed |