Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 6/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748056 | 0.91 | SMN1; SMN2 (0.48) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL13748054 | 0.91 | SLC6A9 (0.47) | ENPP2SLC6A9KCNH2CCR1 | |
| SCHEMBL13749100 | 0.88 | SLC6A9 (0.42) | ALDH1A1ENPP2SLC6A9KCNH2PKM | |
| SCHEMBL13748065 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTSLC6A9KCNH2PKM | |
| SCHEMBL13748458 | 0.86 | SLC6A9 (0.44) | ALDH1A1ENPP2SLC6A9KCNH2PKM | |
| SCHEMBL13748801 | 0.86 | SLC6A9 (0.41) | ALDH1A1MAPTSLC6A9KCNH2PKM | |
| SCHEMBL13748459 | 0.86 | SLC6A9 (0.44) | ALDH1A1ENPP2SLC6A9KCNH2PKM | |
| SCHEMBL13749141 | 0.86 | SLC6A9 (0.43) | ALDH1A1MAPTENPP2SLC6A9KCNH2 | |
| SCHEMBL13748980 | 0.86 | SLC6A9 (0.41) | ALDH1A1MAPTSLC6A9KCNH2PKM | |
| SCHEMBL13748067 | 0.85 | SLC6A9 (0.40) | ALDH1A1ENPP2SLC6A9KCNH2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100120-A2 | PYRIDINYL-SUBSTITUTED PIPERAZINYL OXOETHYL TETRAHYDROPYRAZOLOPYRIDINES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |