Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 9/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13749100 | 0.89 | SLC6A9 (0.42) | SLC6A9KCNH2PDK2ENPP2CHRM4 | |
| SCHEMBL13748801 | 0.87 | SLC6A9 (0.41) | SLC6A9KCNH2PDK2KMT2AKDM4E | |
| SCHEMBL13748458 | 0.87 | SLC6A9 (0.44) | SLC6A9KCNH2PDK2ENPP2CHRM4 | |
| SCHEMBL13748331 | 0.86 | ALDH1A1 (0.47) | SLC6A9KCNH2ENPP2KMT2AMEN1 | |
| SCHEMBL13749141 | 0.86 | SLC6A9 (0.43) | SLC6A9KCNH2PDK2ENPP2CHRM4 | |
| SCHEMBL13748980 | 0.86 | SLC6A9 (0.41) | SLC6A9KCNH2PDK2KMT2AKDM4E | |
| SCHEMBL13749140 | 0.85 | SLC6A9 (0.41) | SLC6A9KCNH2PDK2ENPP2TLR9 | |
| SCHEMBL13749042 | 0.85 | SLC6A9 (0.41) | SLC6A9KCNH2PDK2KMT2AALDH1A1 | |
| SCHEMBL13749198 | 0.85 | SLC6A9 (0.45) | SLC6A9KCNH2PDK2F10 | |
| SCHEMBL13748066 | 0.85 | SLC6A9 (0.43) | SLC6A9KCNH2KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100120-A2 | PYRIDINYL-SUBSTITUTED PIPERAZINYL OXOETHYL TETRAHYDROPYRAZOLOPYRIDINES | NEUROGEN CORPORATION (US) | 2009-08-13 | — | — | WO | disclosed |