Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HMBS | P08397 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163704 | 0.81 | BRD4 (0.44) | BRD4ALOX15ALDH1A1KDM4EGAA | |
| SCHEMBL23952159 | 0.81 | GAA (0.54) | BRD4ALDH1A1KDM4EGAACREBBP | |
| SCHEMBL18415314 | 0.79 | CREBBP (0.63) | BRD4ALOX15ALDH1A1KDM4EGAA | |
| SCHEMBL21180765 | 0.77 | ALDH1A1 (0.42) | BRD4ALOX15ALDH1A1KDM4EGAA | |
| SCHEMBL20094767 | 0.76 | DAO (0.49) | BRD4ALOX15ALDH1A1KDM4EGAA | |
| SCHEMBL25782683 | 0.73 | ALOX15 (0.44) | ALOX15KDM4EGAALMNAMAPT | |
| SCHEMBL19672566 | 0.72 | TDP1 (0.49) | BRD4KDM4EGAAMAPT | |
| SCHEMBL2148753 | 0.72 | GABRP (0.51) | ALOX15ALDH1A1KDM4EGAALMNA | |
| SCHEMBL13692394 | 0.71 | — | — | |
| SCHEMBL1337277 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |
| US-7576117-B1 | Cyclic amine CCR3 antagonist | TEIJIN LIMITED (JP) | 2009-08-18 | — | — | US | disclosed |