Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23952006 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4EGAABRD4CREBBP | |
| SCHEMBL25567051 | 0.81 | CREBBP (0.58) | ALDH1A1KDM4EGAABRD4ALOX15 | |
| SCHEMBL163704 | 0.77 | BRD4 (0.44) | ALDH1A1KDM4EGAABRD4ALOX15 | |
| SCHEMBL13753894 | 0.77 | BRD4 (0.44) | ALDH1A1KDM4EGAABRD4ALOX15 | |
| SCHEMBL18665439 | 0.75 | CREBBP (0.37) | ALDH1A1KDM4EGAABRD4CREBBP | |
| SCHEMBL1969597 | 0.74 | TDP1 (0.51) | GAAALOX15PKMRAB9ASMN1; SMN2 | |
| SCHEMBL1969064 | 0.74 | ALDH1A1 (0.55) | ALDH1A1GAALMNACYP1A2 | |
| SCHEMBL18415350 | 0.73 | SMN1; SMN2 (0.49) | GAAALOX15RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL20094767 | 0.72 | DAO (0.49) | ALDH1A1KDM4EGAABRD4ALOX15 | |
| SCHEMBL25782683 | 0.69 | ALOX15 (0.44) | KDM4EGAAALOX15L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091993-A1 | WATER-SOLUBLE SALTS OF DNA BINDING AGENTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-05-25 | — | — | WO | disclosed |
| US-10358439-B2 | DNA binding agents with a minor groove binding tail | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10358439-B2 | DNA binding agents with a minor groove binding tail | TOP2B, TOP2A, TOP1 | ALDH1A1 2807/4885KDM4E 4024/4885GAA 1285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.