Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19604773 | 0.81 | ALOX5 (0.50) | ALOX5MT-CO2LMNAALDH1A1PKM | |
| SCHEMBL12964166 | 0.80 | LMNA (0.55) | ALOX5MT-CO2LMNATSHRALDH1A1 | |
| SCHEMBL20796167 | 0.79 | ADAM17 (0.70) | LMNATSHRALDH1A1ADAM17PKM | |
| SCHEMBL12659412 | 0.79 | ALOX5 (0.52) | ALOX5MT-CO2LMNAALDH1A1PKM | |
| SCHEMBL12252783 | 0.77 | LMNA (0.52) | LMNATSHRALDH1A1ADAM17PKM | |
| SCHEMBL25497714 | 0.76 | MT-CO2 (0.49) | ALOX5MT-CO2LMNAALDH1A1PKM | |
| SCHEMBL20796475 | 0.75 | MT-CO2 (0.48) | ALOX5MT-CO2TSHRALDH1A1PKM | |
| SCHEMBL14866141 | 0.75 | ALDH1A1 (0.56) | ALOX5MT-CO2LMNATSHRALDH1A1 | |
| SCHEMBL10082605 | 0.73 | ALDH1A1 (0.60) | ALOX5LMNATSHRALDH1A1TDP1 | |
| SCHEMBL12672408 | 0.69 | ALOX5 (0.48) | ALOX5MT-CO2LMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098147-A2 | CONJUGATED MOLECULES COMPRISING A PEPTIDE DERIVED FROM THE CD4 RECEPTOR COUPLED TO A POLYANION FOR THE TREATMENT OF AIDS | INSTITUT PASTEUR (FR) | 2009-08-13 | — | — | WO | disclosed |