Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373736 | 0.84 | RAB9A (0.43) | ALDH1A1RAB9AKDM4ENPC1MEN1 | |
| SCHEMBL1375494 | 0.82 | MET (0.52) | ALDH1A1KDM4EHSD17B10HPGDALOX15 | |
| SCHEMBL1375781 | 0.81 | ALDH1A1 (0.40) | ALDH1A1RAB9AKDM4ENPC1HSD17B10 | |
| SCHEMBL1376319 | 0.78 | ELANE (0.44) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL3517555 | 0.76 | ELANE (0.49) | ALDH1A1KDM4EHPGDGAATSHR | |
| SCHEMBL1372818 | 0.76 | AHR (0.55) | ALDH1A1KDM4EHSD17B10KMT2AHPGD | |
| SCHEMBL1373580 | 0.76 | RAB9A (0.41) | ALDH1A1RAB9AKDM4ENPC1MEN1 | |
| SCHEMBL1376548 | 0.76 | ELANE (0.43) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HPGD | |
| SCHEMBL2782842 | 0.73 | ALDH1A1 (0.54) | ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL16410105 | 0.73 | ALDH1A1 (0.61) | ALDH1A1RAB9ASMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394995-B1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| EP-2394995-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | Kumiai Chemical Industry CO., LTD. (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | CBR3, CBR1, CHRM1 | ALDH1A1 623/4885RAB9A 3900/4885SMN1; SMN2 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.