Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 3/20 | 0.35 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13451133 | 0.81 | PDE2A (0.40) | L3MBTL1KMT2APOLBLMNAAPP | |
| SCHEMBL13755397 | 0.76 | MEN1 (0.39) | L3MBTL1KMT2APOLBLMNACYP4F2 | |
| SCHEMBL6745174 | 0.73 | PDE2A (0.46) | L3MBTL1LMNAKDM4ECYP3A4HSD17B10 | |
| SCHEMBL13755382 | 0.73 | STING1 (0.38) | L3MBTL1KMT2ALMNAAPPCYP1A2 | |
| SCHEMBL13755362 | 0.72 | STING1 (0.45) | KMT2ALMNACYP1A2TNFSTING1 | |
| SCHEMBL28788158 | 0.72 | MAPT (0.52) | L3MBTL1KMT2APOLBLMNAKDM4E | |
| SCHEMBL13755359 | 0.71 | CYP4F2 (0.47) | LMNACYP1A2TNFCYP4F2CYP4A11 | |
| SCHEMBL16796703 | 0.71 | NLRP3 (0.46) | L3MBTL1KMT2APOLBAPPCYP1A2 | |
| SCHEMBL16796779 | 0.71 | CYP4F2 (0.45) | LMNACYP4F2CYP4A11 | |
| SCHEMBL28080073 | 0.70 | L3MBTL1 (0.45) | L3MBTL1KMT2APOLBAPPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7575785-B2 | use thereof in liquid-crystalline media, and and to electro-optical display elements containing these liquid-crystalline media; negative dielectric anisotropy | MERCK PATENT GMBH (DE) | 2009-08-18 | — | — | US | disclosed |
| US-7575785-B2 | use thereof in liquid-crystalline media, and and to electro-optical display elements containing these liquid-crystalline media; negative dielectric anisotropy | MERCK PATENT GMBH (DE) | 2009-08-18 | — | — | US | disclosed |