Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13451247 | 0.86 | NPSR1 (0.38) | MEN1KMT2AALOX5SMN1; SMN2LMNA | |
| SCHEMBL13755398 | 0.84 | SLC1A3 (0.42) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13755360 | 0.76 | L3MBTL1 (0.39) | KMT2ALMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL27911729 | 0.73 | F10 (0.43) | ALOX5SMN1; SMN2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9139647 | 0.70 | ALOX5 (0.50) | ALOX5SMN1; SMN2LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL27493267 | 0.68 | ALDH1A1 (0.61) | MEN1KMT2AALOX5SMN1; SMN2LMNA | |
| SCHEMBL21274457 | 0.67 | LTA4H (0.47) | MEN1KMT2AALOX5SMN1; SMN2LMNA | |
| SCHEMBL21274456 | 0.67 | LTA4H (0.47) | MEN1KMT2AALOX5SMN1; SMN2LMNA | |
| SCHEMBL9785898 | 0.67 | ALDH1A1 (0.49) | MEN1KMT2AALOX5SMN1; SMN2LMNA | |
| SCHEMBL27346466 | 0.67 | ALDH1A1 (0.47) | MEN1KMT2ASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7575785-B2 | use thereof in liquid-crystalline media, and and to electro-optical display elements containing these liquid-crystalline media; negative dielectric anisotropy | MERCK PATENT GMBH (DE) | 2009-08-18 | — | — | US | disclosed |
| US-7575785-B2 | use thereof in liquid-crystalline media, and and to electro-optical display elements containing these liquid-crystalline media; negative dielectric anisotropy | MERCK PATENT GMBH (DE) | 2009-08-18 | — | — | US | disclosed |