Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 12/20 | 0.51 |
| ▸ | HTR2C | P28335 | 12/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13759248 | 0.84 | MAPK14 (0.49) | HTR2AHTR2C | |
| SCHEMBL13759001 | 0.78 | KDR (0.49) | HTR2AHTR2C | |
| SCHEMBL13759252 | 0.77 | POLB (0.51) | HTR2AHTR2C | |
| SCHEMBL14530476 | 0.77 | HRH3 (0.55) | HRH3HTR2AHTR2CCNR1 | |
| SCHEMBL13759251 | 0.74 | MAPK14 (0.51) | — | |
| SCHEMBL13759253 | 0.74 | KDR (0.46) | — | |
| SCHEMBL430172 | 0.73 | EPHX2 (0.57) | HRH3HTR2AHTR2CCNR1 | |
| SCHEMBL14530221 | 0.73 | KMT2A (0.44) | — | |
| SCHEMBL13758989 | 0.69 | HTT (0.52) | HTR2AHTR2C | |
| SCHEMBL13759250 | 0.67 | ALDH1A1 (0.57) | HRH3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100406-A2 | TOPICAL FORMULATIONS FOR THE TREATMENT OF PSORIASIS | SYNTA PHARMACEUTICALS CORP. (US) | 2009-08-13 | — | — | WO | disclosed |