SCHEMBL13765663

SCHEMBL13765663

Fc1ccc2ccc3cc(-c4ccc(I)cc4)c(F)c(F)c3c2c1F

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.34
PTGS2 P35354 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13760089 0.83 PTGS2 (0.40) MIFPTGS2
SCHEMBL13765672 0.78
SCHEMBL13765668 0.74
SCHEMBL26705390 0.71 GPR84 (0.38)
SCHEMBL13760085 0.68 PTGS2 (0.36) MIFPTGS2
SCHEMBL13765702 0.67 ACHE (0.30)
SCHEMBL19985634 0.64 PTGS2 (0.36) MIFPTGS2
SCHEMBL15684587 0.63 PDGFRB (0.36) PTGS2
SCHEMBL8932519 0.62 ADORA3 (0.40) PTGS2
SCHEMBL31711745 0.62 HPRT1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7560147-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2009-07-14 US disclosed
US-20080193681-A1 Liquid-Crystal Medium MERCK PATENT GMBH (DE) 2008-08-14 US disclosed