Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL184552 | 0.84 | MAPT (0.57) | MAPTKMT2AHSD17B2TSHRCA1 | |
| SCHEMBL13767644 | 0.78 | NOTUM (0.49) | MAPTKMT2AHSD17B2TSHRCA1 | |
| SCHEMBL1017686 | 0.78 | RAB9A (0.52) | MAPTKMT2ATSHRCA1CA2 | |
| SCHEMBL2827834 | 0.75 | ALDH1A1 (0.47) | MAPTKMT2ACA1CA2CA12 | |
| SCHEMBL5161173 | 0.75 | HSD17B2 (0.66) | MAPTKMT2AHSD17B2TSHRCA1 | |
| Veratric Acid Methyl Ester SCHEMBL2371276 | 0.74 | MAPT (0.70) | MAPTKMT2ATSHRCA1CA2 | |
| SCHEMBL11059045 | 0.74 | HIF1A (0.47) | MAPTKMT2ATSHRCA1CA2 | |
| SCHEMBL31156002 | 0.74 | MAPT (0.51) | MAPTKMT2ACA1CA2CA12 | |
| SCHEMBL4518140 | 0.73 | GABRA1 (0.43) | MAPTKMT2AHSD17B2TSHRCA1 | |
| Veratric Acid Methyl Ester SCHEMBL3661352 | 0.73 | MAPT (0.73) | MAPTKMT2ATSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090191183-A1 | SUBSTITUTED INDOLES | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090191183-A1 | SUBSTITUTED INDOLES | CYSLTR1, LTB4R, LTB4R2 | MAPT 4476/4885KMT2A 4317/4885HSD17B2 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.