SCHEMBL5390429

SCHEMBL5390429

O=C(C1=C(c2ccccc2)C(=O)c2ccccc2C1=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
LMNA P02545 5/20 1.00
NPSR1 Q6W5P4 5/20 1.00
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
XBP1 P17861 2/20 1.00
HKDC1 Q2TB90 2/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
HSP90AA1 P07900 6/20 0.67
HSP90AB1 P08238 4/20 0.67
FGFR1 P11362 5/20 0.61
FGFR2 P21802 5/20 0.61
FGFR4 P22455 5/20 0.61
FGFR3 P22607 5/20 0.61
SRC P12931 3/20 0.57
CRHBP P24387 1/20 0.57
CRHR2 Q13324 1/20 0.57
MAPT P10636 6/20 0.51
HTT P42858 5/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30885094 0.94 LMNA (0.88) ALDH1A1LMNANPSR1MEN1KMT2A
SCHEMBL17969765 0.89 MEN1 (0.79) ALDH1A1LMNANPSR1MEN1KMT2A
SCHEMBL21470360 0.89 MEN1 (0.79) ALDH1A1LMNANPSR1MEN1KMT2A
SCHEMBL8147516 0.86 LMNA (0.75) ALDH1A1LMNANPSR1MEN1KMT2A
SCHEMBL7099523 0.86 MEN1 (0.75) ALDH1A1LMNANPSR1MEN1KMT2A
SCHEMBL17969764 0.85 LMNA (0.73) ALDH1A1LMNANPSR1MEN1KMT2A
SCHEMBL7099261 0.85 LMNA (0.73) ALDH1A1LMNANPSR1MEN1KMT2A
SCHEMBL29001210 0.85 MEN1 (0.72) ALDH1A1LMNANPSR1MEN1KMT2A
SCHEMBL8018163 0.84 LMNA (0.71) ALDH1A1LMNANPSR1MEN1KMT2A
SCHEMBL17969757 0.83 MEN1 (0.71) ALDH1A1LMNANPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103713481-B Positively charged mono-layer electronic photographic photoreceptor and image processing system 京瓷办公信息系统株式会社 2018-03-30 CN claimed
US-9285692-B2 Positively-charged single-layer electrophotographic photoreceptor and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2016-03-15 US claimed
CN-103713481-A Positively-charged single-layer electrophotographic photoreceptor and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC 2014-04-09 CN claimed
US-7291429-B2 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-11-06 US claimed
CN-1324027-C Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives SAMSUNG ELECTRONICS CO LTD (KR) 2007-07-04 CN claimed
US-20050112482-A1 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives SAMSUNG ELECTRONICS CO., LTD. (KR) 2005-05-26 US claimed
US-10761440-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-09-01 US disclosed
US-20190310562-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-10-10 US disclosed
CN-103713481-B Positively charged mono-layer electronic photographic photoreceptor and image processing system 京瓷办公信息系统株式会社 2018-03-30 CN disclosed
US-9785062-B2 Positively chargeable single-layer electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-10-10 US disclosed
US-9785062-B2 Positively chargeable single-layer electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-10-10 US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-9760029-B2 Electrophotographic photosensitive member, image forming apparatus, and process cartridge KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-09-12 US disclosed
US-6127076-A ELECTROPHOTOSENSITIVE MATERIAL CONTAINING NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE DERIVATIVE AS ELECTRON TRANSPORTING AGENT KYOCERA MITA CORPORATION (JP) 2000-10-03 US disclosed
US-6063534-A CHARGE TRANSPORTING AGENTS HAVING A HIGH PHOTOSENSITIVITY, A LOW RESIDUAL POTENTIAL AND CAPABLE OF STABLY FORMING A HIGHLY-DENSE VIVID IMAGE WITHOUT BACKGROUND FOGGING; 2-PHENYL-3-NITRO-SUBSTITUTED HYDROCARBYLOXO-)NAPHTHAQUINONES MITA INDUSTRIAL CO., LTD. (JP) 2000-05-16 US disclosed
US-6022658-A SENSITIVE ELECTRON TRANSFERRING COMPOUND MITA INDUSTRIAL CO LTD. (JP) 2000-02-08 US disclosed
EP-0962458-A1 New naphthalenetetracarboxylic acid diimides as electron transporting agents in photosensitive material for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1999-12-08 EP disclosed
US-5994012-A CHARGE GENERATING COMPOUND, CHARGE TRANSFER COMPOUND AND BINDER MITA INDUSTRIAL CO., LTD. (JP) 1999-11-30 US disclosed
US-5863688-A REACTING 1,3-INDANDIONE DERIVATIVE WITH A BROMOACETIC ESTER TO FORM 1,3-INDANDIONE ESTER, ISOMERIZING THE ESTER DERIVATIVE IN PRESENCE OF SODIUM HYDRIDE TO FORM NAPHTHOIC ESTER, OXIDIZING TO FORM NAPHTHOQUINONE DERIVATIVE MITA INDUSTRIAL CO., LTD (JP) 1999-01-26 US disclosed
EP-0764886-A2 Naphthoquinone derivative and electrophotosensitive material using the same MITA INDUSTRIAL CO. LTD. (JP) 1997-03-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050112482-A1 Naphthalenetetracarboxylic acid diimide derivatives and electrophotographic photoconductive material using the derivatives ADSL, DCLK1, DCLK2 ALDH1A1 425/4885LMNA 383/4885NPSR1 3076/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.