Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | NPR3 | P17342 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2219871 | 0.80 | POLB (0.72) | POLBCSNK2A1MAP3K5AURKAAURKB | |
| SCHEMBL3246720 | 0.78 | POLB (0.68) | POLBCSNK2A1MAP3K5AURKAAURKB | |
| SCHEMBL13771495 | 0.74 | ALDH1A1 (0.64) | POLBCSNK2A1MAP3K5AURKAAURKB | |
| SCHEMBL3243500 | 0.71 | MAP3K5 (0.60) | POLBMAP3K5AURKAAURKBSCN9A | |
| SCHEMBL12443884 | 0.69 | MAP3K5 (0.63) | POLBCSNK2A1MAP3K5AURKAAURKB | |
| SCHEMBL12515414 | 0.68 | MAP3K5 (0.58) | POLBCSNK2A1MAP3K5AURKAAURKB | |
| SCHEMBL13921831 | 0.67 | RAB9A (0.51) | SYK | |
| SCHEMBL21925740 | 0.67 | MAP3K5 (0.59) | POLBCSNK2A1MAP3K5AURKAAURKB | |
| SCHEMBL16928500 | 0.65 | MAP3K5 (0.54) | POLBCSNK2A1MAP3K5AURKAAURKB | |
| SCHEMBL21635739 | 0.65 | RHOA (0.66) | CSNK2A1MAP3K5JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093041-A2 | MODIFIED CELLULOSIC MATERIALS | THE SECRETARY OF STATE F0R DEFENCE (GB) | 2009-07-30 | — | — | WO | disclosed |