Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1F | P30939 | 1/20 | 0.47 |
| ▸ | CCNT1 | O60563 | 5/20 | 0.44 |
| ▸ | CDK9 | P50750 | 5/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.38 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13776993 | 0.80 | HTR1A (0.52) | HTR1AHTR1DHTR1FSLC10A2 | |
| SCHEMBL3087627 | 0.72 | OPRD1 (0.39) | CCNT1CDK9OPRD1OPRM1OPRK1 | |
| SCHEMBL3087623 | 0.72 | OPRD1 (0.39) | CCNT1CDK9OPRD1OPRM1OPRK1 | |
| SCHEMBL13776994 | 0.72 | HTR1A (0.50) | HTR1AHTR1DHTR1FUTS2R | |
| SCHEMBL14208685 | 0.69 | HTR1A (0.56) | HTR1AHTR1DHTR1F | |
| SCHEMBL14417925 | 0.69 | HTR1A (0.49) | HTR1AHTR1DHTR1FSIGMAR1 | |
| SCHEMBL2264538 | 0.69 | KDM4E (0.60) | HTR1AHTR1DHTR1FCCNT1CDK9 | |
| SCHEMBL2934570 | 0.69 | KDM4E (0.60) | HTR1AHTR1DHTR1FOPRM1OPRK1 | |
| SCHEMBL4492625 | 0.67 | CHRNB2 (0.40) | OPRD1OPRM1OPRK1BRD4DRD1 | |
| SCHEMBL13627337 | 0.67 | CHRNB2 (0.40) | OPRD1OPRM1OPRK1BRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090192157-A1 | INDOLE COMPOUNDS AND METHODS FOR TREATING VISCERAL PAIN | NEURAXON, INC. (CA) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192157-A1 | INDOLE COMPOUNDS AND METHODS FOR TREATING VISCERAL PAIN | TPH1, NOS1, IDO1 | HTR1A 8/4885HTR1D 6/4885HTR1F 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.