SCHEMBL13777366

SCHEMBL13777366

O=[SH](=O)NCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.48
CA12 O43570 2/20 0.48
CA7 P43166 2/20 0.48
CA14 Q9ULX7 2/20 0.48
ADH1B P00325 1/20 0.48
ADH1C P00326 1/20 0.48
ADH1A P07327 1/20 0.48
ADH7 P40394 1/20 0.48
IDO1 P14902 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
THRB P10828 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MAPT P10636 3/20 0.46
CYP3A4 P08684 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CA1 P00915 2/20 0.45
KEAP1 Q14145 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ALOX12 P18054 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15840092 0.76 SMN1; SMN2 (0.46) CA2CA12IDO1MEN1KMT2A
SCHEMBL27827507 0.76 CA2 (0.45) CA2CA12CA7CA14ADH1B
SCHEMBL15876410 0.76 TGM2 (0.44) CA2CA12MEN1KMT2AMAPT
SCHEMBL15418809 0.76 MEN1 (0.52) IDO1MEN1KMT2AALDH1A1HPGD
SCHEMBL19991861 0.76
SCHEMBL17434647 0.76 SIGMAR1 (0.54) CA2CA12IDO1MEN1KMT2A
SCHEMBL13777371 0.76 LMNA (0.52) IDO1KMT2AALDH1A1HPGDTP53
SCHEMBL27698277 0.76 KMT2A (0.58) MEN1KMT2AHSD17B10ALDH1A1HPGD
SCHEMBL16090747 0.76 CA2 (0.52) CA2MEN1KMT2ATDP1MAPT
SCHEMBL17103657 0.74 CHRM2 (0.53) IDO1CYP3A4TP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798210-B Preparation method of high-purity glycolide 山东金特安全科技有限公司 2025-05-20 CN claimed
CN-119798210-A Preparation method of high-purity glycolide 山东金特安全科技有限公司 2025-04-11 CN claimed
CN-119315103-A Rechargeable magnesium battery electrolyte and preparation method thereof 东北大学秦皇岛分校 2025-01-14 CN claimed
US-20230266302-A1 SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES THE UNIV OF TULSA (US) 2023-08-24 US claimed
EP-4185706-A1 SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES The University Of Tulsa (US) 2023-05-31 EP claimed
CN-113527152-A Biphenylsulfonamide compound and method for preventing and treating crop pests by using same 西北农林科技大学 2021-10-22 CN claimed
CN-110963967-B Preparation method of 2-methyl-4-aminoquinoline 武汉智顿科技发展有限公司 2021-02-12 CN claimed
CN-110963967-A Preparation method of 2-methyl-4-aminoquinoline 武汉智顿科技发展有限公司 2020-04-07 CN claimed
CN-119798210-B Preparation method of high-purity glycolide 山东金特安全科技有限公司 2025-05-20 CN disclosed
CN-119798210-A Preparation method of high-purity glycolide 山东金特安全科技有限公司 2025-04-11 CN disclosed
US-20250093329-A1 SCREENING OF COMPOUNDS THE UNIVERSITY OF TULSA 2025-03-20 US disclosed
CN-112494657-B Sulfonamide linkers, conjugates thereof and methods of making 西纳福克斯股份有限公司 2025-02-11 CN disclosed
CN-119315103-A Rechargeable magnesium battery electrolyte and preparation method thereof 东北大学秦皇岛分校 2025-01-14 CN disclosed
EP-4469592-A1 SCREENING OF COMPOUNDS The University Of Tulsa (US) 2024-12-04 EP disclosed
US-20090170861-A1 Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors SCHERING CORPORATION AND ALBANY MOLECULAR RESEARCH, INC. 2009-07-02 US disclosed
US-20090170861-A1 Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors SCHERING CORPORATION AND ALBANY MOLECULAR RESEARCH, INC. 2009-07-02 US disclosed
WO-2009017671-A1 SYNTHESIS OF INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 VITAE PHARMACEUTICALS, INC. (US) 2009-02-05 WO disclosed
US-7459455-B2 Pyrimidine compounds SMITHKLINE BEECHAM CORPORATION (US) 2008-12-02 US disclosed
CN-1026048-C Use of solsonylurea compounds as herbicide TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1994-10-05 CN disclosed
CN-1059073-A Solsonylurea compounds is as the purposes of weed killer herbicide TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1992-03-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170861-A1 Pyridazinone Derivatives Useful as Glucan Synthase Inhibitors MAN2A1, GYS2, MANBA CA2 3206/4885CA12 4603/4885CA7 3760/4885
US-20230266302-A1 SYNTHESIS AND USE OF N-BENZYL SULFONAMIDES ATP5ME, ATP5F1B, ATP5MG CA2 2378/4885CA12 3134/4885CA7 2170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.