Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1378229 | 0.92 | HPGD (0.38) | ALDH1A1HPGDNPC1LMNAHTT | |
| SCHEMBL1378327 | 0.80 | KMT2A (0.53) | ALDH1A1HPGDNPC1HTTHDAC6 | |
| SCHEMBL6865989 | 0.78 | ACHE (0.41) | NPC1LMNAEPHX1RAB9A | |
| SCHEMBL5305861 | 0.78 | HPGD (0.45) | ALDH1A1HPGDLMNAHSD11B1SMN1; SMN2 | |
| SCHEMBL28950573 | 0.78 | HDAC6 (0.60) | ALDH1A1HPGDNPC1LMNAHTT | |
| SCHEMBL25913609 | 0.77 | SCN1A (0.48) | ALDH1A1HPGDNPC1LMNAHTT | |
| SCHEMBL5305864 | 0.77 | PARP1 (0.44) | HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL24848168 | 0.76 | MEN1 (0.46) | ALDH1A1NPC1LMNAHTTEPHX1 | |
| SCHEMBL5010378 | 0.76 | PARP10 (0.44) | ALDH1A1NPC1LMNAHTTRAB9A | |
| SCHEMBL25920617 | 0.75 | LMNA (0.56) | NPC1LMNAHTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4658940-B2 | — | — | 2011-03-23 | — | — | JP | claimed |
| JP-2006528213-A | — | — | 2006-12-14 | — | — | JP | claimed |
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | claimed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | claimed |
| EP-1636216-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004101553-A1 | BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |