Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MLNR | O43193 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5305864 | 0.84 | PARP1 (0.44) | HPGDHSD17B10TP53KDM4EMEN1 | |
| SCHEMBL1378229 | 0.78 | HPGD (0.38) | HPGDHSD17B10TP53KDM4EMEN1 | |
| SCHEMBL1378233 | 0.78 | ALDH1A1 (0.45) | HPGDKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL6878640 | 0.78 | HTR1A (0.41) | HPGDHSD17B10TP53KDM4EMEN1 | |
| SCHEMBL8294487 | 0.74 | KDM4E (0.61) | HPGDHSD17B10TP53KDM4EMEN1 | |
| SCHEMBL25920617 | 0.72 | LMNA (0.56) | TP53MEN1CHRM2CHRM3KMT2A | |
| SCHEMBL536590 | 0.70 | KDM4E (0.46) | HPGDHSD17B10KDM4EMEN1KMT2A | |
| Potassium SCHEMBL29729324 | 0.69 | KDM4E (0.45) | HPGDHSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL25913609 | 0.69 | SCN1A (0.48) | HPGDMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL24848168 | 0.68 | MEN1 (0.46) | TP53MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007028524-A2 | USE OF A DERIVATIVE OF IMIDAZOLE FOR THE TREATMENT OF LEUKOTRIENE RELATED DISORDERS | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH S.A. (ES) | 2007-03-15 | — | — | WO | claimed |
| WO-2007028524-A2 | USE OF A DERIVATIVE OF IMIDAZOLE FOR THE TREATMENT OF LEUKOTRIENE RELATED DISORDERS | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH S.A. (ES) | 2007-03-15 | — | — | WO | disclosed |