Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4313186 | 1.00 | PKM (0.40) | PKMPKLRTSHRGFERPSEN1 | |
| SCHEMBL10272543 | 0.77 | NPSR1 (0.52) | PKMPKLRTSHRLMNAALDH1A1 | |
| SCHEMBL4309319 | 0.75 | TSHR (0.47) | PKMPKLRTSHRGFERPSEN1 | |
| SCHEMBL5098948 | 0.73 | ALDH1A1 (0.40) | PKMPKLRTSHRALDH1A1POLB | |
| SCHEMBL4317996 | 0.72 | TSHR (0.47) | PKMPKLRTSHRGFERPSEN1 | |
| SCHEMBL13784249 | 0.71 | CTSK (0.39) | PKMPKLRTSHRGFERPSEN1 | |
| Hydrochloric Acid SCHEMBL4312468 | 0.71 | TSHR (0.46) | PKMPKLRTSHRGFERPSEN1 | |
| SCHEMBL25246410 | 0.70 | CHRNB2 (0.48) | PKMPKLRTSHRGFERPSEN1 | |
| SCHEMBL1847833 | 0.70 | PKM (0.56) | PKMPKLRTSHRLMNAALDH1A1 | |
| SCHEMBL5983334 | 0.69 | PKM (0.35) | PKMPKLRPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |
| US-7563784-B2 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-21 | — | — | US | disclosed |