Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23031291 | 0.82 | THRB (0.49) | THRBTSHRHTTACHECA1 | |
| SCHEMBL31312824 | 0.81 | THRB (0.41) | THRBTSHRACHEL3MBTL1ALDH1A1 | |
| SCHEMBL2403793 | 0.81 | THRB (0.53) | THRBTSHRACHEL3MBTL1ALDH1A1 | |
| SCHEMBL13872030 | 0.81 | THRB (0.53) | THRBTSHRACHEL3MBTL1ALDH1A1 | |
| SCHEMBL586950 | 0.80 | THRB (0.42) | THRBTSHRLMNAACHEKMT2A | |
| SCHEMBL23031233 | 0.80 | THRB (0.42) | THRBTSHRHTTLMNAKMT2A | |
| SCHEMBL24036478 | 0.79 | TGM2 (0.42) | THRBTSHRACHEL3MBTL1ALDH1A1 | |
| SCHEMBL11837277 | 0.78 | THRB (0.43) | THRBTSHRGAAHTTKMT2A | |
| SCHEMBL10057616 | 0.78 | TSHR (0.53) | THRBTSHRHTTACHEPOLB | |
| SCHEMBL14984891 | 0.78 | THRB (0.46) | THRBTSHRGAAACHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12083194-B2 | Dental materials based on polymerizable thiourea derivatives | IVOCLAR VIVADENT AG (LI) | 2024-09-10 | — | — | US | disclosed |
| EP-4039220-B1 | DENTAL MATERIALS ON THE BASIS OF POLYMERISABLE THIOUREA DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2022-12-28 | — | — | EP | disclosed |
| EP-4039220-B1 | DENTAL MATERIALS ON THE BASIS OF POLYMERISABLE THIOUREA DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2022-12-28 | — | — | EP | disclosed |
| US-20220257474-A1 | Dental Materials Based On Polymerizable Thiourea Derivatives | IVOCLAR VIVADENT AG (LI) | 2022-08-18 | — | — | US | disclosed |
| EP-4039220-A1 | DENTAL MATERIALS ON THE BASIS OF POLYMERISABLE THIOUREA DERIVATIVES | Ivoclar Vivadent AG (LI) | 2022-08-10 | — | — | EP | disclosed |
| US-7541393-B2 | Composition containing a polymerizable reducing agent, kit, and method | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-06-02 | — | — | US | disclosed |
| US-20070088096-A1 | COMPOSITION CONTAINING A POLYMERIZABLE REDUCING AGENT, KIT, AND METHOD | 3M INNOVATIVE PROPERTIES COMPANY | 2007-04-19 | — | — | US | disclosed |
| US-7173074-B2 | Composition containing a polymerizable reducing agent, kit, and method | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220257474-A1 | Dental Materials Based On Polymerizable Thiourea Derivatives | TAS2R10, PAM, HBG1 | THRB 231/4885TSHR 508/4885GAA 2781/4885 |
| US-12083194-B2 | Dental materials based on polymerizable thiourea derivatives | TAS2R10, PAM, HBG1 | THRB 231/4885TSHR 508/4885GAA 2781/4885 |
| US-20070088096-A1 | COMPOSITION CONTAINING A POLYMERIZABLE REDUCING AGENT, KIT, AND METHOD | KIT, TST, SETDB1 | THRB 3991/4885TSHR 3886/4885GAA 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.