Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MMP1 | P03956 | 4/20 | 0.63 |
| ▸ | MMP2 | P08253 | 4/20 | 0.63 |
| ▸ | MMP9 | P14780 | 4/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482451 | 0.86 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNAALDH1A1MAPTGAA | |
| SCHEMBL1866821 | 0.83 | LMNA (0.50) | SMN1; SMN2LMNAALDH1A1MAPTGAA | |
| SCHEMBL22536077 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAALDH1A1MAPTGAA | |
| SCHEMBL1859426 | 0.82 | MAPK3 (0.49) | SMN1; SMN2LMNAALDH1A1MAPTGAA | |
| SCHEMBL2093160 | 0.82 | ALDH1A1 (0.62) | SMN1; SMN2LMNAALDH1A1MAPTGAA | |
| SCHEMBL3182061 | 0.81 | TGM2 (0.49) | SMN1; SMN2LMNAALDH1A1MAPTGAA | |
| SCHEMBL613090 | 0.81 | TGM2 (0.65) | SMN1; SMN2LMNAALDH1A1MAPTEGFR | |
| SCHEMBL31228347 | 0.81 | TGM2 (0.65) | SMN1; SMN2LMNAALDH1A1MAPTEGFR | |
| SCHEMBL299233 | 0.80 | ALDH1A1 (0.60) | SMN1; SMN2LMNAALDH1A1MAPTGAA | |
| SCHEMBL3182066 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2LMNAALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466789-A | Synthesis method of beta-trifluoromethylthioamide participated by silver trifluormethane | 陕西先氟领创科技有限公司 | 2024-01-30 | — | — | CN | claimed |
| JP-4828407-B2 | — | — | 2011-11-30 | — | — | JP | claimed |
| EP-1594869-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | Targacept, Inc. (US) | 2005-11-16 | — | — | EP | claimed |
| WO-2004076449-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | TARGACEPT, INC. (US) | 2004-09-10 | — | — | WO | claimed |
| CN-118515580-A | Synthesis and anti-tumor activity research of novel adamantane structure-containing drug small molecules | 长春工业大学 | 2024-08-20 | — | — | CN | disclosed |
| EP-4351553-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH (DE) | 2024-04-17 | — | — | EP | disclosed |
| CN-117466789-A | Synthesis method of beta-trifluoromethylthioamide participated by silver trifluormethane | 陕西先氟领创科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2022258792-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2022-12-15 | — | — | WO | disclosed |
| CN-110498761-A | Acetyl amantadine piperazine (pyridine) class compound is as neuroprotection agent application | SHANGHAI INST PHARMACEUTICAL IND | 2019-11-26 | — | — | CN | disclosed |
| WO-2013085802-A1 | PYRROLOPYRIMIDINES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-06-13 | — | — | WO | disclosed |
| EP-1594869-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | Targacept, Inc. (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004076449-A2 | 3-SUBSTITUTED-2(ARYLALKYL)-1-AZABICYCLOALKANES AND METHODS OF USE THEREOF | TARGACEPT, INC. (US) | 2004-09-10 | — | — | WO | disclosed |
| US-3974238-A | CROSSLINKED POLYBUTADIENE | ACUSHNET COMPANY (US) | 1976-08-10 | — | — | US | disclosed |