Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13798014 | 0.81 | GRM5 (0.32) | USP7CNR2 | |
| SCHEMBL13811096 | 0.81 | MAPK1 (0.44) | USP7CNR2NPC1RAB9AIDO1 | |
| SCHEMBL29549206 | 0.78 | GRM5 (0.41) | CYP2A6NPC1RAB9A | |
| SCHEMBL22533036 | 0.78 | GRM5 (0.41) | CYP2A6NPC1RAB9A | |
| SCHEMBL19385063 | 0.77 | RAB9A (0.45) | USP7MAP4K4NPC1RAB9AATM | |
| SCHEMBL10896655 | 0.77 | USP7 (0.53) | USP7CNR2CYP2A6EGLN1TRPA1 | |
| SCHEMBL20068878 | 0.77 | USP7 (0.53) | USP7CNR2CYP2A6EGLN1TRPA1 | |
| SCHEMBL2322615 | 0.76 | LTA4H (0.43) | EGLN1MAP4K4NPC1RAB9A | |
| SCHEMBL1915601 | 0.74 | USP7 (0.58) | USP7CNR2CYP2A6EGLN1MAP4K4 | |
| SCHEMBL10264753 | 0.74 | USP7 (0.50) | USP7CNR2CYP2A6EGLN1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553798-B2 | Heterocyclic carboxamides with microbiocidal activity | SYNGENTA CROP PROTECTION, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-7553798-B2 | Heterocyclic carboxamides with microbiocidal activity | SYNGENTA CROP PROTECTION, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | SYNGENTA CROP PROTECTION, INC. (US) | 2008-06-05 | — | — | US | disclosed |
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | SYNGENTA CROP PROTECTION, INC. (US) | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132557-A1 | Heterocyclic Carboxamides with Microbiocidal Activity | MPO, FPR1, CD14 | USP7 1996/4885CNR2 71/4885CYP2A6 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.