Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | HTR2C | P28335 | 5/20 | 0.46 |
| ▸ | HTR2B | P41595 | 5/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 11/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525564 | 0.92 | HTR2A (0.46) | HTR2AHTR2CHTR2BPNMTDRD2 | |
| SCHEMBL14346890 | 0.84 | SLC6A4 (0.47) | HTR2AHTR2CHTR2BPNMTSLC6A4 | |
| SCHEMBL24242574 | 0.84 | SLC6A4 (0.47) | HTR2AHTR2CHTR2BPNMTSLC6A4 | |
| SCHEMBL10247281 | 0.81 | DRD3 (0.62) | DRD2DRD3HTR1ADRD4 | |
| SCHEMBL10247150 | 0.81 | DRD3 (0.62) | DRD2DRD3HTR1ADRD4 | |
| SCHEMBL597666 | 0.78 | SRD5A1 (0.42) | HTR2AHTR2CHTR2BDRD2DRD3 | |
| SCHEMBL14525576 | 0.78 | HTR2C (0.38) | HTR2AHTR2CHTR2BPNMTSLC6A4 | |
| SCHEMBL14741406 | 0.78 | SRD5A1 (0.41) | HTR2AHTR2CHTR2BSRD5A1SRD5A2 | |
| SCHEMBL16233582 | 0.77 | HTR1D (0.46) | HTR2AHTR2CHTR2BDRD2DRD3 | |
| SCHEMBL16233587 | 0.77 | PNMT (0.47) | HTR2AHTR2CHTR2BPNMTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-04 | — | — | US | disclosed |
| US-9326513-B2 | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2016-05-03 | — | — | US | disclosed |
| US-20140335201-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-13 | — | — | US | disclosed |
| US-8623407-B2 | Gabapentin-containing solid compositions and process for preparing the same | PFIZER INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8623407-B2 | Gabapentin-containing solid compositions and process for preparing the same | PFIZER INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20090156677-A1 | Gabapentin-containing Solid Compositions and Process for Preparing the Same | PFIZER INC | 2009-06-18 | — | — | US | disclosed |
| US-20090156677-A1 | Gabapentin-containing Solid Compositions and Process for Preparing the Same | PFIZER INC | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156677-A1 | Gabapentin-containing Solid Compositions and Process for Preparing the Same | GABRD, GABRA6, GABRB1 | HTR2A 1444/4885HTR2C 1326/4885HTR2B 1129/4885 |
| US-20140335201-A1 | FUNGICIDAL COMPOSITIONS | CYP1B1, CYP4B1, DDT | HTR2A 3428/4885HTR2C 2732/4885HTR2B 1485/4885 |
| US-20160219879-A1 | FUNGICIDAL COMPOSITIONS | CYP1B1, CYP4B1, DDT | HTR2A 3428/4885HTR2C 2732/4885HTR2B 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.