Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132096 | 0.87 | RAB9A (0.59) | SMN1; SMN2ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL13799598 | 0.83 | LDHA (0.51) | SMN1; SMN2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL4294190 | 0.83 | RAB9A (0.66) | SMN1; SMN2ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL4148882 | 0.81 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL19926302 | 0.81 | LDHA (0.52) | SMN1; SMN2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL12600109 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL4137342 | 0.78 | LCK (0.55) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL19986341 | 0.77 | LDHA (0.52) | SMN1; SMN2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL19275145 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL8031624 | 0.77 | LDHA (0.51) | SMN1; SMN2ALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156590-A1 | Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process for Making Them, and Use Thereof for Treating Pain and Other Conditions | GRUENENTHAL GMBH (DE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156590-A1 | Vanilloid Receptor Ligands, Pharmaceutical Compositions Containing Them, Process for Making Them, and Use Thereof for Treating Pain and Other Conditions | TRPV1, OPRL1, TRPV2 | SMN1; SMN2 3235/4885ALDH1A1 1590/4885KMT2A 4539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.