Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 10/20 | 0.47 |
| ▸ | NPC1 | O15118 | 9/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19926302 | 0.93 | LDHA (0.52) | LDHARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL23932781 | 0.85 | LDHA (0.52) | LDHARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL13799596 | 0.77 | SMN1; SMN2 (0.49) | LDHARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL8031624 | 0.76 | LDHA (0.51) | LDHARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL13799598 | 0.73 | LDHA (0.51) | LDHARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL19926175 | 0.73 | OGA (0.43) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL30521463 | 0.72 | SMN1; SMN2 (0.54) | LDHARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL25804734 | 0.72 | SMN1; SMN2 (0.54) | LDHARAB9ANPC1KMT2AMEN1 | |
| SCHEMBL19926229 | 0.72 | ALOX15 (0.55) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL12600109 | 0.72 | ALDH1A1 (0.47) | LDHARAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079753-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | SERVIER PHARMACEUTICALS LLC | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079753-A1 | INHIBITORS OF CELLULAR METABOLIC PROCESSES | MNAT1, MAT2A, PCK2 | LDHA 580/4885RAB9A 512/4885NPC1 2877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.