Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3646978 | 0.98 | HDAC1 (0.40) | HDAC1HDAC6PTGS2ADRA2AADRA2B | |
| SCHEMBL30963214 | 0.77 | PTGS2 (0.38) | HDAC1HDAC6PTGS2ADRA2AADRA2B | |
| SCHEMBL3646973 | 0.77 | PTGS2 (0.38) | HDAC1HDAC6PTGS2ADRA2AADRA2B | |
| Lithium Ion SCHEMBL15231782 | 0.77 | PTGS2 (0.38) | HDAC1HDAC6PTGS2ADRA2AADRA2B | |
| SCHEMBL25702790 | 0.74 | NAPRT (0.45) | ADRA2AADRA2BADRA2CSMN1; SMN2KCNQ3 | |
| SCHEMBL20692254 | 0.74 | CHRNA7 (0.33) | KDM4E | |
| SCHEMBL13801197 | 0.74 | NNMT (0.49) | KDM4EKMT2AMAPT | |
| SCHEMBL1463872 | 0.72 | NAPRT (0.44) | ADRA2AADRA2BADRA2CSMN1; SMN2KCNQ3 | |
| SCHEMBL1463875 | 0.72 | NAPRT (0.44) | ADRA2AADRA2BADRA2CSMN1; SMN2KMT2A | |
| SCHEMBL3646787 | 0.72 | NNMT (0.47) | KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014074715-A1 | CYCLOPROPYL AMIDE DERIVATIVES | GENENTECH, INC. (US) | 2014-05-15 | — | — | WO | disclosed |
| US-20090156642-A1 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156642-A1 | 5-Membered heterocyclic compound | CEL, PGA5, COG5 | HDAC1 466/4885HDAC6 63/4885PTGS2 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.