Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.72 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | ACHE | P22303 | 1/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.57 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.57 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28393 | 0.84 | SIGMAR1 (1.00) | SIGMAR1ACHECHRNB2CHRNB4CHRNA3 | |
| SCHEMBL894920 | 0.84 | SIGMAR1 (1.00) | SIGMAR1ACHECHRNB2CHRNB4CHRNA3 | |
| Piperazine SCHEMBL28228981 | 0.82 | SIGMAR1 (0.96) | SIGMAR1ACHECHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL1597474 | 0.82 | SIGMAR1 (0.96) | SIGMAR1ACHECHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9644712 | 0.82 | SIGMAR1 (0.96) | SIGMAR1ACHEHPGD | |
| SCHEMBL10254838 | 0.82 | L3MBTL3 (0.61) | SIGMAR1L3MBTL3L3MBTL1ACHEEPHX1 | |
| Piperazine SCHEMBL27760905 | 0.81 | SIGMAR1 (0.93) | SIGMAR1ACHECHRNB2CHRNB4CHRNA3 | |
| SCHEMBL8988831 | 0.81 | ACHE (0.69) | SIGMAR1L3MBTL3L3MBTL1ACHEEPHX1 | |
| Benzoic Acid SCHEMBL18838596 | 0.80 | TSHR (0.56) | SIGMAR1L3MBTL3L3MBTL1CHRNB2CHRNB4 | |
| SCHEMBL4003983 | 0.80 | ACHE (0.73) | SIGMAR1L3MBTL3L3MBTL1ACHEEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | DR. KARL THOMAE GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7498325-B2 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | KARL THOMAS GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| EP-1440976-B1 | Modified aminoacids, pharmaceuticals containing these compounds and method for their production | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163480-A1 | Modified amino acids, pharmaceuticals containing these compounds and method for their production | PTMS, CHRM1, SRMS | SIGMAR1 377/4885L3MBTL3 2960/4885L3MBTL1 2352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.