Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | VCP | P55072 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22887391 | 0.78 | CASP3 (0.68) | KDRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL426115 | 0.77 | NPC1 (0.62) | KDRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL7030607 | 0.76 | FLT3 (0.57) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL423127 | 0.75 | FLT3 (0.61) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL27613442 | 0.74 | NPC1 (0.53) | KDRNPC1RAB9AVCPMEN1 | |
| SCHEMBL22887217 | 0.74 | NPC1 (0.53) | KDRNPC1RAB9AVCPMEN1 | |
| SCHEMBL13814181 | 0.74 | CASP3 (0.54) | KDRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6438025 | 0.74 | NPC1 (0.53) | KDRNPC1RAB9AVCPMEN1 | |
| SCHEMBL8304969 | 0.72 | NPC1 (0.80) | KDRNPC1RAB9AVCPMEN1 | |
| SCHEMBL430192 | 0.72 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090142832-A1 | Indoles, Derivatives, and Analogs Thereof and Uses Therefor | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090142832-A1 | Indoles, Derivatives, and Analogs Thereof and Uses Therefor | TUBB, TUBB1, TUBB6 | KDR 4063/4885NPC1 1555/4885RAB9A 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.