Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801608 | 0.90 | KDM4E (0.47) | LMNASMN1; SMN2HTTCYP1A2CYP2D6 | |
| SCHEMBL13801657 | 0.77 | LMNA (0.43) | LMNASMN1; SMN2HTTCYP1A2CYP2D6 | |
| SCHEMBL13801822 | 0.75 | HDAC8 (0.42) | LMNASMN1; SMN2CYP1A2CYP2D6KDM4E | |
| SCHEMBL23016004 | 0.73 | GAA (0.61) | LMNASMN1; SMN2KDM4EHDAC8MAPT | |
| SCHEMBL7634561 | 0.73 | GAA (0.61) | LMNASMN1; SMN2KDM4EHDAC8MAPT | |
| SCHEMBL21392344 | 0.71 | KDM4E (0.58) | LMNASMN1; SMN2KDM4EHDAC8MAPT | |
| Bicarbonate SCHEMBL11086979 | 0.70 | P2RX7 (0.55) | SMN1; SMN2HTTKDM4EHDAC8MAPT | |
| SCHEMBL27228563 | 0.68 | LMNA (0.48) | LMNASMN1; SMN2CYP1A2KDM4EHDAC8 | |
| SCHEMBL5608474 | 0.67 | HDAC8 (0.59) | LMNASMN1; SMN2KDM4EHDAC8MAPT | |
| SCHEMBL27849930 | 0.67 | GAA (0.62) | LMNASMN1; SMN2KDM4EHDAC8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245123-B1 | METHODS FOR PRODUCING ALKYLATED 1,3 BENZENEDIAMINE COMPOUNDS | CHEMTURA CORP (US) | 2017-07-19 | — | — | EP | disclosed |
| WO-2009076091-A2 | ALKYLATED 1,3 BENZENEDIAMINE COMPOUNDS AND METHODS FOR PRODUCING SAME | CHEMTURA CORPORATION (US) | 2009-06-18 | — | — | WO | disclosed |